Evidence map›Paper›PMID 29808264›Full record

ReviewPediatric nephrology (Berlin, Germany)2019

Neonatal hypertension: cases, causes, and clinical approach.

Michelle C Starr, Joseph T Flynn

Erratum issued Registry-linked trialAbstract readCase ReportsReview
In one paragraph

Review in Pediatric nephrology (Berlin, Germany), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT07547917 (Improving the Measurement of Neonatal High Blood Pressure Using the Boppli Device), which is not on this map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07547917 naenrolling by invitationnot on this mapstarted 2026, after this paper: background citation

Improving the Measurement of Neonatal High Blood Pressure Using the Boppli Device

TypeinterventionalSponsorIndiana UniversityRan2026 to 2031Enrolled30ConditionsHypertension, NeonatalArmsBoppli
3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Perioperative Management of Paediatric Hypertension.Children (Basel, Switzerland) · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Pediatric Hypertension: A Condition That Matters.Children (Basel, Switzerland) · 2024
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Michelle C StarrDivision of Nephrology, Department of Pediatrics, Seattle Children's Hospital and University of Washington School of Medicine, 4800 Sand Point Way NE, M/S OC.9.820, Seattle, WA, 98105, USA.
Joseph T FlynnDivision of Nephrology, Department of Pediatrics, Seattle Children's Hospital and University of Washington School of Medicine, 4800 Sand Point Way NE, M/S OC.9.820, Seattle, WA, 98105, USA. joseph.flynn@seattlechildrens.org.

Funding

Pediatric Nephrology Training ProgramT32DK007662 · NIDDK · UNIVERSITY OF WASHINGTON · PI HINGORANI, SANGEETA · 1991 to 2020
$5.5M
NIDDK NIH HHS T32 DK007662
6 · The paper itself

Abstract

Neonatal hypertension is increasingly recognized as dramatic improvements in neonatal intensive care, advancements in our understanding of neonatal physiology, and implementation of new therapies have led to improved survival of premature infants. A variety of factors appear to be important in determining blood pressure in neonates, including gestational age, birth weight, and postmenstrual age. Normative data on neonatal blood pressure values remain limited. The cause of hypertension in an affected neonate is often identified with careful diagnostic evaluation, with the most common causes being umbilical catheter-associated thrombosis, renal parenchymal disease, and chronic lung disease. Clinical expertise may need to be relied upon to decide the best approach to treatment in such patients, as data on the use of antihypertensive medications in this age group are extremely limited. Available data suggest that long-term outcomes are usually good, with resolution of hypertension in most infants. In this review, we will take a case-based approach to illustrate these concepts and to point out important evidence gaps that need to be addressed so that management of neonatal hypertension may be improved.

Indexed as

Administration, IntravenousAntihypertensive AgentsBirth WeightBlood PressureBlood Pressure DeterminationClinical Decision-MakingGestational AgeHumansHydralazineHypertensionIncidenceInfant, NewbornInfant, Newborn, DiseasesInfant, PrematureIntensive Care Units, NeonatalKidneyAntihypertensive AgentsHydralazineLabetalolAntihypertensive therapyChronic lung diseaseKidney diseaseNeonatePrematurity

Identifiers

PMID29808264
PMCPMC6261698

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.