Evidence map›Paper›PMID 29848486›Full record

ArticleGenetics2018

Human-Mediated Introgression of Haplotypes in a Modern Dairy Cattle Breed.

Qianqian Zhang, Mario P L Calus, Mirte Bosse, Goutam Sahana, Mogens Sandø Lund, Bernt Guldbrandtsen

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Qianqian ZhangCenter for Quantitative Genetics and Genomics, Department of Molecular Biology and Genetics, Aarhus University, Denmark Qianqian.zhang@mbg.au.dk.ORCID 0000-0002-4423-1236
Mario P L CalusAnimal Breeding and Genomics, Wageningen University & Research, The Netherlands.ORCID 0000-0002-3213-704X
Mirte BosseAnimal Breeding and Genomics, Wageningen University & Research, The Netherlands.
Goutam SahanaCenter for Quantitative Genetics and Genomics, Department of Molecular Biology and Genetics, Aarhus University, Denmark.ORCID 0000-0001-7608-7577
Mogens Sandø LundCenter for Quantitative Genetics and Genomics, Department of Molecular Biology and Genetics, Aarhus University, Denmark.
Bernt GuldbrandtsenCenter for Quantitative Genetics and Genomics, Department of Molecular Biology and Genetics, Aarhus University, Denmark.
Aarhus University · DKWageningen University & Research · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Domestic animals can serve as model systems of adaptive introgression and their genomic signatures. In part, their usefulness as model systems is due to their well-known histories. Different breeding strategies such as introgression and artificial selection have generated numerous desirable phenotypes and superior performance in domestic animals. The modern Danish Red Dairy Cattle is studied as an example of an introgressed population. It originates from crossing the traditional Danish Red Dairy Cattle with the Holstein and Brown Swiss breeds, both known for high milk production. This crossing happened, among other things due to changes in the production system, to raise milk production and overall performance. The genomes of modern Danish Red Dairy Cattle are heavily influenced by regions introgressed from the Holstein and Brown Swiss breeds and under subsequent selection in the admixed population. The introgressed proportion of the genome was found to be highly variable across the genome. Haplotypes introgressed from Holstein and Brown Swiss contained or overlapped known genes affecting milk production, as well as protein and fat content (

Indexed as

Quantitative Trait LociSelection, GeneticAnimalsAnimals, DomesticBreedingCattleFemaleGenetics, PopulationHaplotypesHumansPhenotypehigh-yielding cattle breedsmodern dairy cattle breedselective introgressionsignature of selection

Identifiers

PMID29848486
PMCPMC6063242
OpenAlexW2807585514

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.