Evidence map›Paper›PMID 29849622›Full record

ArticleInternational journal of endocrinology2018

Circulating MicroRNAs in Elderly Type 2 Diabetic Patients.

Giuseppina Catanzaro, Zein Mersini Besharat, Martina Chiacchiarini, Luana Abballe, Claudia Sabato, Alessandra Vacca, Paola Borgiani, Francesco Dotta, Manfredi Tesauro, Agnese Po and 1 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in International journal of endocrinology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04856683 (PRecisiOn MEdicine to Target Frailty of Endocrine-metabolic Origin), which is not on this map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04856683 unknown statusnot on this mapstarted 2020, after this paper: background citation

PRecisiOn MEdicine to Target Frailty of Endocrine-metabolic Origin

TypeobservationalSponsorUniversity of Roma La SapienzaRan2020 to 2024Enrolled1,100ConditionsFrailty
3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Circulating Nucleic Acid-Based Biomarkers of Type 2 Diabetes.International journal of molecular sciences · 2021
    Review
  15. Article
  16. Article
  17. MicroRNAs, Parkinson's Disease, and Diabetes Mellitus.International journal of molecular sciences · 2021
    Review
  18. miR-720 Regulates Insulin Secretion by Targeting Rab35.BioMed research international · 2021
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Giuseppina CatanzaroDepartment of Experimental Medicine, Sapienza University of Rome, Rome, Italy.
Zein Mersini BesharatDepartment of Experimental Medicine, Sapienza University of Rome, Rome, Italy.ORCID 0000-0003-0317-9854
Martina ChiacchiariniDepartment of Molecular Medicine, Sapienza University of Rome, Rome, Italy.ORCID 0000-0001-9229-0372
Luana AbballeDepartment of Experimental Medicine, Sapienza University of Rome, Rome, Italy.ORCID 0000-0003-4446-2293
Claudia SabatoDepartment of Molecular Medicine, Sapienza University of Rome, Rome, Italy.ORCID 0000-0001-7533-4660
Alessandra VaccaDepartment of Experimental Medicine, Sapienza University of Rome, Rome, Italy.ORCID 0000-0002-0006-5379
Paola BorgianiDepartment of Biomedicine and Prevention, Tor Vergata University, Rome, Italy.
Francesco DottaFondazione Umberto Di Mario ONLUS, Rome, Italy.ORCID 0000-0003-4947-7478
Manfredi TesauroHypertension and Nephrology Unit, Department of Systems Medicine, Tor Vergata University, Rome, Italy.ORCID 0000-0002-3967-1552
Agnese PoDepartment of Molecular Medicine, Sapienza University of Rome, Rome, Italy.ORCID 0000-0002-9346-8782
Elisabetta FerrettiDepartment of Experimental Medicine, Sapienza University of Rome, Rome, Italy.ORCID 0000-0001-7265-6429
Sapienza University of Rome · ITUniversity of Rome Tor Vergata · ITFondazione Umberto Di Mario · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The circulating microRNAs (miRNAs) associated with type 2 diabetes (T2D) in elderly patients are still being defined. To identify novel miRNA biomarker candidates for monitoring responses to sitagliptin in such patients, we prospectively studied 40 T2D patients (age > 65) with HbA1c levels of 7.5-9.0% on metformin. After collection of baseline blood samples (

Identifiers

PMID29849622
PMCPMC5914089
OpenAlexW2797009218

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.