Evidence map›Paper›PMID 29851159›Full record

ArticleClinical transplantation2018

Metformin use in the first year after kidney transplant, correlates, and associated outcomes in diabetic transplant recipients: A retrospective analysis of integrated registry and pharmacy claims data.

L S Vest, F M Koraishy, Z Zhang, N N Lam, M A Schnitzler, V R Dharnidharka, D Axelrod, A S Naik, T A Alhamad, B L Kasiske and 2 more

Abstract read
In one paragraph

Article in Clinical transplantation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. International consensus on post-transplantation diabetes mellitus.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2024
    Article
  10. Review
  11. Observational
  12. KDOQI US Commentary on the KDIGO 2020 Clinical Practice Guideline for Diabetes Management in CKD.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2022
    Article
  13. Review
  14. Review
  15. Diabetes mellitus in dialysis and renal transplantation.Therapeutic advances in endocrinology and metabolism · 2021
    Review
  16. Article
  17. Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 2 countries.

L S VestSaint Louis University, St. Louis, MO, USA.
F M KoraishySaint Louis University, St. Louis, MO, USA.
Z ZhangSaint Louis University, St. Louis, MO, USA.
N N LamUniversity of Alberta, Edmonton, AB, Canada.
M A SchnitzlerSaint Louis University, St. Louis, MO, USA.
V R DharnidharkaWashington University, St. Louis, MO, USA.
D AxelrodLahey Clinic, Burlington, MA, USA.
A S NaikUniv Michigan, Ann Arbor, MI, USA.
T A AlhamadWashington University, St. Louis, MO, USA.
B L KasiskeHennepin County, Minneapolis, MN, USA.
G P HessSymphony Health, Conshohocken, PN, USA.
K L LentineSaint Louis University, St. Louis, MO, USA.ORCID 0000-0002-9423-4849
Saint Louis University · USWashington University in St. Louis · USHennepin County · USLahey Hospital and Medical Center · USMacula Vision Research Foundation · USUniversity of Alberta · CAUniversity of Michigan · US

Funding

Choosing Immune Suppression in Renal Transplantation by Efficacy and MorbidityR01DK102981 · NIDDK · WASHINGTON UNIVERSITY · PI DHARNIDHARKA, VIKAS R. · 2014 to 2018
$1.9M
NIDDK NIH HHS R01 DK102981
6 · The paper itself

Abstract

While guidelines support metformin as a therapeutic option for diabetic patients with mild-to-moderate renal insufficiency, the frequency and outcomes of metformin use in kidney transplant recipients are not well described. We integrated national U.S. transplant registry data with records from a large pharmaceutical claims clearinghouse (2008-2015). Associations (adjusted hazard ratio,

Indexed as

Postoperative ComplicationsAdolescentAdultChildDiabetes Mellitus, Type 2FemaleFollow-Up StudiesGlomerular Filtration RateGraft RejectionGraft SurvivalHumansHypoglycemic AgentsInsurance, Pharmaceutical ServicesKidney Failure, ChronicKidney Function TestsKidney TransplantationHypoglycemic AgentsMetformindiabetes mellituskidney transplantmetforminmortalitypharmacy claimsrisk factors

Identifiers

PMID29851159
PMCPMC6122956
OpenAlexW2807310966

What Socratic holds

Texttitle and abstract
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.