Evidence map›Paper›PMID 29855567›Full record

ArticleScientific reports2018

Interaction of hepatic stellate cells with neutrophils and macrophages in the liver following oncogenic kras activation in transgenic zebrafish.

Qiqi Yang, Chuan Yan, Zhiyuan Gong

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Review
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  4. Precision immune regulation in KRAS-mutated cancers: the final piece of the puzzle?Journal of experimental & clinical cancer research : CR · 2025
    Review
  5. Article
  6. Methods to Study Liver Disease Using Zebrafish Larvae.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  7. Review
  8. Article
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  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Qiqi YangDepartment of Biological Sciences, National University of Singapore, Singapore, Singapore.
Chuan YanDepartment of Biological Sciences, National University of Singapore, Singapore, Singapore.
Zhiyuan GongDepartment of Biological Sciences, National University of Singapore, Singapore, Singapore. dbsgzy@nus.edu.sg.ORCID 0000-0002-9660-5260
National University of Singapore · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Activation of hepatic stellate cells (HSC) plays a crucial role in the liver disease progression from liver fibrosis/cirrhosis to cancer. Here, we found a rapid change of microenvironment after kras

Indexed as

AnimalsAnimals, Genetically ModifiedHepatic Stellate CellsHepatocytesIndolesLiverLiver NeoplasmsMacrophagesNeutrophilsProto-Oncogene Proteins p21(ras)Receptor, Serotonin, 5-HT2BSerotoninSignal TransductionTransforming Growth Factor beta1Tumor MicroenvironmentUp-RegulationIndolesN-(1-methyl-5-indolyl)-N'-(3-methyl-5-isothiazolyl)ureaProto-Oncogene Proteins p21(ras)Receptor, Serotonin, 5-HT2BSerotoninTransforming Growth Factor beta1UreaZebrafish Proteins

Identifiers

PMID29855567
PMCPMC5981472
OpenAlexW2805697505

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.