Evidence map›Paper›PMID 29868209›Full record

ReviewGlobal health, epidemiology and genomics2016

Changing phenotype and disease behaviour of chronic pancreatitis in India: evidence for gene-environment interactions.

P K Garg, D Narayana

Open access · goldAbstract readReview
In one paragraph

Review in Global health, epidemiology and genomics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

  1. Assessing the burden and trends of pancreatitis in India from 1990-2021: An analysis of the global burden of disease database.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026
    Article
  2. L-arginine-induced chronic pancreatitis in mice: Evaluating effects of pirfenidone and simvastatin.World journal of gastrointestinal pharmacology and therapeutics · 2025
    Article
  3. Article
  4. Article
  5. Review
  6. Idiopathic chronic pancreatitis: Beyond antioxidants.World journal of gastroenterology · 2021
    Article
  7. Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

P K GargDepartment of Gastroenterology, All India Institute of Medical Sciences, New Delhi, India.
D NarayanaState Planning Board, Government of Kerala, India.
All India Institute of Medical Sciences · INGovernment of Kerala · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe idiopathic variety of chronic pancreatitis (CP) in India particularly in Kerala state was earlier called 'tropical pancreatitis' with peculiar features: early age of onset, severe malnutrition, diabetes and poor prognosis. A change in disease phenotype and behaviour has been observed recently.

objectiveTo review the changing profile of CP in India and examine its relationship with environmental influences and socio-economic development.

methodsRelevant studies on CP in India were reviewed along with social and economic parameters in Kerala over the past 4 decades.

resultsThere has been a definite change in the phenotype of CP in India with onset in mid twenties, better nutritional status, and a much better prognosis compared with the reports in 1970s. Genetic susceptibility due to genetic mutations particularly in

conclusionChanging profile of CP in India and better understanding of risk factors provide evidence for gene-environmental interactions in its pathobiology.

Indexed as

Chronic pancreatitisphenotypeSPINK1tropical pancreatitis

Identifiers

PMID29868209
PMCPMC5870434
OpenAlexW2534140764

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.