Evidence map›Paper›PMID 29872118›Full record

ReviewNature reviews. Gastroenterology & hepatology2018

Clinical measurement of gastrointestinal motility and function: who, when and which test?

Mark R Fox, Peter J Kahrilas, Sabine Roman, C Prakash Gyawali, S Mark Scott, Satish S Rao, Jutta Keller, Michael Camilleri, International Working Group for Disorders of Gastrointestinal Motility and Function

Open access · greenAbstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Gastroenterology & hepatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 71 citations in OpenAlex.

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  10. Feature tracking-based motility analysis of excised intestinal tissue using video recordings.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 5 countries.

Mark R FoxAbdominal Center: Gastroenterology, St. Claraspital, Basel, Switzerland. dr.mark.fox@gmail.com.ORCID http://orcid.org/0000-0003-4394-5584
Peter J KahrilasDivision of Gastroenterology and Hepatology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Sabine RomanDigestive Physiology, Hospices Civils de Lyon, and Lyon I University, and INSERM U1032, LabTAU, Lyon, France.
C Prakash GyawaliDivision of Gastroenterology, Washington University School of Medicine, St. Louis, MO, USA.ORCID http://orcid.org/0000-0002-3388-0660
S Mark ScottWingate Institute of Neurogastroenterology and GI Physiology Unit, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Satish S RaoDivision of Gastroenterology and Hepatology, Augusta University, Augusta, Georgia, GA, USA.
Jutta KellerDepartment of Internal Medicine, Israelitic Hospital, Academic Hospital of the University of Hamburg, Hamburg, Germany.
Michael CamilleriDivision of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.
International Working Group for Disorders of Gastrointestinal Motility and Function
Queen Mary University of London · GBUniversität Hamburg · DEUniversité Claude Bernard Lyon 1 · FRMayo Clinic in Arizona · USNorthwestern University · USUniversity Hospital of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Symptoms related to abnormal gastrointestinal motility and function are common. Oropharyngeal and oesophageal dysphagia, heartburn, bloating, abdominal pain and alterations in bowel habits are among the most frequent reasons for seeking medical attention from internists or general practitioners and are also common reasons for referral to gastroenterologists and colorectal surgeons. However, the nonspecific nature of gastrointestinal symptoms, the absence of a definitive diagnosis on routine investigations (such as endoscopy, radiology or blood tests) and the lack of specific treatments make disease management challenging. Advances in technology have driven progress in the understanding of many of these conditions. This Review serves as an introduction to a series of Consensus Statements on the clinical measurements of gastrointestinal motility, function and sensitivity. A structured, evidence-based approach to the initial assessment and empirical treatment of patients presenting with gastrointestinal symptoms is discussed, followed by an outline of the contribution of modern physiological measurement on the management of patients in whom the cause of symptoms has not been identified with other tests. Discussions include the indications for and utility of high-resolution manometry, ambulatory pH-impedance monitoring, gastric emptying studies, breath tests and investigations of anorectal structure and function in day-to-day practice and clinical management.

Indexed as

Deglutition DisordersGastric EmptyingGastroesophageal RefluxGastrointestinal DiseasesGastrointestinal MotilityHumansRectal Diseases

Identifiers

PMID29872118
OpenAlexW2806190750

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.