Observational studyObesity surgery2018
The Impact of Obesity and Metabolic Surgery on Chronic Inflammation.
Observational study in Obesity surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT02697695 (Impact of Obesity and Metabolic Surgery on Chronic Inflammation), which is not on this map. Cited by 14 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Impact of Obesity and Metabolic Surgery on Chronic Inflammation
Who cites it
14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 43 citations in OpenAlex.
- Effect of Metabolic and Bariatric Surgery on the Clinical Course of Multiple Sclerosis in Patients with Severe Obesity: a Systematic Review.Obesity surgery · 2023Pooled it
- What Is Weight Loss After Bariatric Surgery Expressed in Percentage Total Weight Loss (%TWL)? A Systematic Review.Obesity surgery · 2021Pooled it
- Temporal Associations Among Body Mass Index, Fasting Insulin, and Systemic Inflammation: A Systematic Review and Meta-analysis.JAMA network open · 2021Pooled it
- Trial
- Surgery for Obesity and Weight-Related Diseases Changes the Inflammatory Profile in Women with Severe Obesity: a Randomized Controlled Clinical Trial.Obesity surgery · 2021Trial
- Anthropometric Changes and Systemic Inflammation After Sleeve Gastrectomy: Do Composite Markers Reflect the Change?Obesity surgery · 2025Article
- Neuroinflammation: A Modifiable Pathway Linking Obesity, Alzheimer's disease, and Depression.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2023Review
- The Evaluation of Serum Endocan, Interleukin-6, and CRP Levels Following Sleeve Gastrectomy.International journal of general medicine · 2023Article
- Does Neutrophil-Lymphocyte Ratio Correlate with the Improvement of Hepatosteatosis after Laparoscopic Sleeve Gastrectomy?Obesity facts · 2022Article
- The relationship between specialized pro-resolving lipid mediators, morbid obesity and weight loss after bariatric surgery.Scientific reports · 2020Article
- The Impact of Bariatric Surgery on Hepatic Function and Predictors of Liver Steatosis and Fibrosis.Obesity surgery · 2020Article
- Weight Reduction for Obesity-Induced Heart Failure with Preserved Ejection Fraction.Current hypertension reports · 2020Review
- Sleeve Gastrectomy Rescuing the Altered Functional Connectivity of Lateral but Not Medial Hypothalamus in Subjects with Obesity.Obesity surgery · 2019Article
- Analysis of inflammatory and metabolic biomarkers in patients submitted to abdominoplasty after bariatric surgery.Acta cirurgica brasileira · 2019Article
Corrections and comments
- Erratum issued
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundObesity and metabolic surgery is known to improve chronic inflammatory status. Whether improvement is related to anatomical changes or weight loss is still to debate.
objectiveThe aim of this clinical trial is to compare the different bariatric procedures sleeve gastrectomy (SG), Roux-en-Y gastric bypass (RYGB), and One-anastomosis gastric bypass (OAGB), pertaining to their effects on inflammation markers.
methodsPatients who underwent SG, RYGB, or OAGB as a primary treatment for severe obesity were included. The data collected preoperatively (T0) and 1, 3, and 6 (T6) months after surgery included gender, weight, comorbidities and toxic habits at baseline, body mass index (BMI), waist circumference, total body weight loss in % (TBWL), leukocyte count in × 10
resultsFour hundred sixty-eight patients were included. Drop-out rate was 25.8% at T6. Preoperatively the mean value of leukocytes and CRP was 7.4 × 10
conclusionCRP but not leukocyte count decreased after all three bariatric procedures but without any significance between the three groups. Surgically induced weight loss and not anatomical changes might play an important role for improvement in chronic inflammation.
trial registrationThe National Clinical Trials number was NCT02697695 ( https://clinicaltrials.gov/ct2/show/NCT02697695 ).
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.