Evidence map›Paper›PMID 29880567›Full record

Trial reportBMJ open2018

Feasibility study to assess the delivery of a lifestyle intervention (TreatWELL) for patients with colorectal cancer undergoing potentially curative treatment.

Maureen Macleod, Robert J C Steele, Ronan E O'Carroll, Mary Wells, Anna Campbell, Jacqui A Sugden, Jackie Rodger, Martine Stead, Jennifer McKell, Annie S Anderson

Abstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMJ open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  5. Review
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  14. Colorectal cancer survivors' beliefs on nutrition and cancer; correlates with nutritional information provision.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Maureen MacleodDivision of Cancer Research, Centre for Research into Cancer Prevention and Screening, University of Dundee, Dundee, UK.
Robert J C SteeleDivision of Cancer Research, Centre for Research into Cancer Prevention and Screening, University of Dundee, Dundee, UK.
Ronan E O'CarrollDivision of Psychology, School of Natural Sciences, University of Stirling, Stirling, UK.
Mary WellsNMAHP Research Unit, University of Stirling, Stirling, UK.ORCID 0000-0001-5789-2773
Anna CampbellDepartment of Sport Exercise and Health Science, School of Applied Science, Edinburgh Napier University, Edinburgh, UK.
Jacqui A SugdenDivision of Cancer Research, Centre for Research into Cancer Prevention and Screening, University of Dundee, Dundee, UK.
Jackie RodgerDivision of Cancer Research, Centre for Research into Cancer Prevention and Screening, University of Dundee, Dundee, UK.
Martine SteadInstitute for Social Marketing, University of Stirling and the Open University, Stirling, UK.
Jennifer McKellInstitute for Social Marketing, University of Stirling and the Open University, Stirling, UK.
Annie S AndersonDivision of Cancer Research, Centre for Research into Cancer Prevention and Screening, University of Dundee, Dundee, UK.

Funding

Chief Scientist Office CZH/4/939
6 · The paper itself

Abstract

objectivesTo assess the feasibility of delivering and evaluating a lifestyle programme for patients with colorectal cancer undergoing potentially curative treatments. STUDY

designNon-randomised feasibility trial.

settingNational Health Service (NHS) Tayside.

participantsAdults with stage I-III colorectal cancer.

interventionThe programme targeted smoking, alcohol, physical activity, diet and weight management. It was delivered in three face-to-face counselling sessions (plus nine phone calls) by lifestyle coaches over three phases (1: presurgery, 2: surgical recovery and 3: post-treatment recovery). PRIMARY OUTCOME: Feasibility measures (recruitment, retention, programme implementation, achieved measures, fidelity, factors affecting protocol adherence and acceptability). SECONDARY OUTCOMES: Measured changes in body weight, waist circumference, walking and self-reported physical activity, diet, smoking, alcohol intake, fatigue, bowel function and quality of life.

resultsOf 84 patients diagnosed, 22 (26%) were recruited and 15 (18%) completed the study. Median time for intervention delivery was 5.5 hours. Coaches reported covering most (>70%) of the intervention components but had difficulties during phase 2. Evaluation measures (except walk test) were achieved by all participants at baseline, and most (<90%) at end of phase 2 and phase 3, but <20% at end of phase 1. Protocol challenges included limited time between diagnosis and surgery and the presence of comorbidities. The intervention was rated highly by participants but limited support from NHS staff was noted. The majority of participants (77%) had a body mass index>25 kg/m

conclusionsTo make this intervention feasible for testing as a full trial, further research is required on (a) recruitment optimisation, (b) appropriate assessment tools, (c) protocols for phase 2 and 3, which can build in flexibility and (d) ways for NHS staff to facilitate the programme. TRIAL REGISTRATION NUMBER: ISRCTN52345929; Post-results.

Indexed as

Life StyleAgedAged, 80 and overBody Mass IndexBody WeightColorectal NeoplasmsDietExerciseFeasibility StudiesFemaleHealth PromotionHumansMaleMiddle AgedQuality of LifeTreatment Outcomecolorectal cancerlifestyle interventionprehabilitation

Identifiers

PMID29880567
PMCPMC6009630

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.