Evidence map›Paper›PMID 29895552›Full record

ArticleJournal of the American Society of Nephrology : JASN2018

Prevention of Fatal C3 Glomerulopathy by Recombinant Complement Receptor of the Ig Superfamily.

Xiaoxu Wang, Menno Van Lookeren Campagne, Kenneth J Katschke, Damodar Gullipalli, Takashi Miwa, Yoshiyasu Ueda, Yuan Wang, Matthew Palmer, Guolan Xing, Wen-Chao Song

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Society of Nephrology : JASN, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Trial
  2. Article
  3. C3 Glomerulopathy: Novel Treatment Paradigms.Kidney international reports · 2024
    Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Emerging immunotherapies for autoimmune kidney disease.Human vaccines & immunotherapeutics · 2019
    Review
  9. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Xiaoxu WangDepartment of Nephrology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Menno Van Lookeren CampagneDepartment of Immunology, Genentech, Inc., San Francisco, California.
Kenneth J KatschkeDepartment of Immunology, Genentech, Inc., San Francisco, California.
Damodar GullipalliDepartments of Systems Pharmacology and Translational Therapeutics and.
Takashi MiwaDepartments of Systems Pharmacology and Translational Therapeutics and.
Yoshiyasu UedaDepartments of Systems Pharmacology and Translational Therapeutics and.
Yuan WangDepartments of Systems Pharmacology and Translational Therapeutics and.
Matthew PalmerPathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania; and.
Guolan XingDepartment of Nephrology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Wen-Chao SongDepartments of Systems Pharmacology and Translational Therapeutics and songwe@pennmedicine.upenn.edu.
Translational Therapeutics (United States) · USFirst Affiliated Hospital of Zhengzhou University · CNUniversity of Pennsylvania · US

Funding

BIOLOGY OF DECAY ACCELERATING FACTORR01AI044970 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI SONG, WENCHAO · 2000 to 2014
$4.9M
Pathogenesis and therapy of dense deposit disease in a mouse modelR01AI085596 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI SONG, WENCHAO · 2010 to 2019
$3.5M
Complement dysregulation and atypical hemolytic uremic syndromeR01AI117410 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI SONG, WENCHAO · 2015 to 2019
$2.0M
NIAID NIH HHS R01 AI044970NIAID NIH HHS R01 AI085596NIAID NIH HHS R01 AI117410
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Analysis of VarianceAnimalsBiopsy, NeedleBlotting, WesternComplement ActivationComplement C3Complement Factor BDisease Models, AnimalGlomerulonephritis, IGAGuanine Nucleotide-Releasing Factor 2ImmunohistochemistryKidney Function TestsMiceMice, Inbred C57BLRandom AllocationReceptors, ComplementComplement C3Complement Factor BGuanine Nucleotide-Releasing Factor 2Receptors, ComplementVSIG4 protein, mousecomplementglomerulopathymembranoproliferative glomerulonephritis (MPGN)

Identifiers

PMID29895552
PMCPMC6065080
OpenAlexW2808545248

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.