Evidence map›Paper›PMID 29910930›Full record

ArticleChemical science2018

A bright FIT-PNA hybridization probe for the hybridization state specific analysis of a C → U RNA edit

Ge-Min Fang, Jasmine Chamiolo, Svenja Kankowski, Felix Hövelmann, Dhana Friedrich, Alexander Löwer, Jochen C Meier, Oliver Seitz

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Gamma-FIT-PNAs as sensitive RNA probes.RSC chemical biology · 2026
    Article
  3. Review
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  17. Nucleic-Acid Structures as Intracellular Probes for Live Cells.Advanced materials (Deerfield Beach, Fla.) · 2020
    Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Ge-Min FangDepartment of Chemistry , Humboldt-Universität zu Berlin , Brook-Taylor-Strasse 2 , D-12489 Berlin , Germany . Email: oliver.seitz@chemie.hu-berlin.de.
Jasmine ChamioloDepartment of Chemistry , Humboldt-Universität zu Berlin , Brook-Taylor-Strasse 2 , D-12489 Berlin , Germany . Email: oliver.seitz@chemie.hu-berlin.de.
Svenja KankowskiZoological Institute , Technical University Braunschweig , Spielmannstr. 7 , D-38106 Braunschweig , Germany.
Felix HövelmannDepartment of Chemistry , Humboldt-Universität zu Berlin , Brook-Taylor-Strasse 2 , D-12489 Berlin , Germany . Email: oliver.seitz@chemie.hu-berlin.de.
Dhana FriedrichMax Delbrück Centrum für Molekulare Medizin , Robert Rössle Straße 10 , 13125 Berlin , Germany.
Alexander LöwerMax Delbrück Centrum für Molekulare Medizin , Robert Rössle Straße 10 , 13125 Berlin , Germany.ORCID 0000-0002-8819-3040
Jochen C MeierZoological Institute , Technical University Braunschweig , Spielmannstr. 7 , D-38106 Braunschweig , Germany.ORCID 0000-0001-5574-3336
Oliver SeitzDepartment of Chemistry , Humboldt-Universität zu Berlin , Brook-Taylor-Strasse 2 , D-12489 Berlin , Germany . Email: oliver.seitz@chemie.hu-berlin.de.ORCID 0000-0003-0611-4810
Humboldt-Universität zu Berlin · DEMax Delbrück Center · DEZoological Institute · RUAnhui University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oligonucleotide probes that show enhanced fluorescence upon nucleic acid hybridization enable the detection and visualization of specific mRNA molecules,

Identifiers

PMID29910930
PMCPMC5982193
OpenAlexW2799454529

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.