Evidence map›Paper›PMID 29924707›Full record

ArticleJournal of neurophysiology2018

Abnormally reduced primary motor cortex output is related to impaired hand function in chronic stroke.

C M Buetefisch, K P Revill, M W Haut, G M Kowalski, M Wischnewski, M Pifer, S R Belagaje, F Nahab, D J Cobia, X Hu and 2 more

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Journal of neurophysiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07150325 (Integration of Force Control Training and Mirror Visual Feedback on Stroke Patients on Brain Activation and Hand Function), which is not on this map. Cited by 26 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 2 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07150325 nacompletednot on this mapstarted 2024, after this paper: background citation

Integration of Force Control Training and Mirror Visual Feedback on Stroke Patients on Brain Activation and Hand Function

TypeinterventionalSponsorNational Cheng-Kung University HospitalRan2024 to 2025Enrolled5ConditionsStroke, Stroke PatientsArmsTIPr, Mirror Visual Feedback Device, Mirror Visual Feedback Device(Blocked mirror)
3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 42 citations in OpenAlex.

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  17. Clinical diagnostic utility of transcranial magnetic stimulation in neurological disorders. Updated report of an IFCN committee.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

C M BuetefischDepartment of Neurology, Emory University , Atlanta, Georgia.
K P RevillDepartment of Psychology, Emory University , Atlanta, Georgia.
M W HautDepartment of Behavioral Medicine and Psychiatry, West Virginia University School of Medicine , Morgantown, West Virginia.
G M KowalskiDepartment of Neurology, Emory University , Atlanta, Georgia.
M WischnewskiDepartment of Neurology, Emory University , Atlanta, Georgia.
M PiferDepartment of Behavioral Medicine and Psychiatry, West Virginia University School of Medicine , Morgantown, West Virginia.
S R BelagajeDepartment of Neurology, Emory University , Atlanta, Georgia.
F NahabDepartment of Neurology, Emory University , Atlanta, Georgia.
D J CobiaDepartment of Psychology and Neuroscience Center, Brigham Young University , Provo, Utah.
X HuDepartment of Bioengineering, University of California Riverside , Riverside, California.
D DrakeDepartment of Biostatistics, The Mailman School of Public Health, Columbia University , New York, New York.
G HobbsDepartment of Statistics, West Virginia University , Morgantown, West Virginia.
Emory University · USWest Virginia University · USBrigham Young University · USColumbia University · USUniversity of California, Riverside · US

Funding

Customized cortical stimulation therapy in the rehabilitation of stroke patientsR01NS090677 · NINDS · EMORY UNIVERSITY · PI BUETEFISCH, CATHRIN M · 2015 to 2018
$3.0M
Reorganizing motor cortex in stroke patient through Hebbian-type stimulationR21HD067906 · NICHD · EMORY UNIVERSITY · PI BUETEFISCH, CATHRIN M · 2011 to 2012
$464k
Enhancing stroke recovery through cortical stimulationR56NS070879 · NINDS · EMORY UNIVERSITY · PI BUETEFISCH, CATHRIN M · 2011 to 2011
$455k
NICHD NIH HHS R21 HD067906NINDS NIH HHS R01 NS090677NINDS NIH HHS R56 NS070879
6 · The paper itself

Abstract

Stroke often involves primary motor cortex (M1) and its corticospinal projections (CST). As hand function is critically dependent on these structures, its recovery is often incomplete. The neuronal substrate supporting affected hand function is not well understood but likely involves reorganized M1 and CST of the lesioned hemisphere (M1

Indexed as

AgedEvoked Potentials, MotorFemaleHandHumansMaleMiddle AgedMotor CortexPyramidal TractsStrokeTranscranial Magnetic Stimulationhumanrehabilitationstroke

Identifiers

PMID29924707
PMCPMC6230804
OpenAlexW2808973346

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.