Evidence map›Paper›PMID 29927872›Full record

GuidelineJournal of pediatric gastroenterology and nutrition2018

Nutritional Considerations in Pediatric Pancreatitis: A Position Paper from the NASPGHAN Pancreas Committee and ESPGHAN Cystic Fibrosis/Pancreas Working Group.

Maisam Abu-El-Haija, Aliye Uc, Steven L Werlin, Alvin Jay Freeman, Miglena Georgieva, Danijela Jojkić-Pavkov, Daina Kalnins, Brigitte Kochavi, Bart G P Koot, Stephanie Van Biervliet and 3 more

Registry-linked trialOpen access · greenAbstract readPractice Guideline
In one paragraph

Guideline in Journal of pediatric gastroenterology and nutrition, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03672422 (Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer), which is not on this map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03672422 completednot on this map

Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer (CPDPC) CPDPC16-03 Pediatric Longitudinal Cohort Study of Chronic Pancreatitis

Typeobservational_patient_registrySponsorAliye UcRan2017 to 2020Enrolled623ConditionsPancreatitis, Chronic, Pancreatitis, AcuteArmsBlood sample, Patient questionnaires, Saliva sample, Urine sample
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 73 citations in OpenAlex.

  1. European guideline on indications, performance and clinical impact ofUnited European gastroenterology journal · 2021
    Guideline
  2. Review
  3. Article
  4. Article
  5. Review
  6. The evolution of nutritional care in children and young people with acute lymphoblastic leukaemia: a narrative review.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2025
    Review
  7. Turkish Society of Gastroenterology: Pancreas Working Group, Acute Pancreatitis Committee Consensus Report.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2024
    Review
  8. Nutritional management guidelines for pancreatitis-a commentary.Hepatobiliary surgery and nutrition · 2024
    Article
  9. Review
  10. Review
  11. An assessment of pancreatology education in North American pediatric gastroenterology fellowship programs.Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] · 2022
    Article
  12. Effect of Early Enteral Nutrition on Serum Inflammatory Factors and Intestinal Mucosal Permeability in Patients with Severe Acute Pancreatitis.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2021
    Article
  13. Article
  14. Article
  15. Article
  16. Observational
  17. Pancreatitis in Children.Gastroenterology · 2019
    Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 11 institutions in 8 countries.

Maisam Abu-El-HaijaDivision of Gastroenterology Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.
Aliye UcStead Family Children's Hospital, University of Iowa, Iowa City, IA.
Steven L WerlinDepartment of Pediatrics, Medical College of Wisconsin, Milwaukee, WI.
Alvin Jay FreemanDivision of Gastroenterology, Hepatology and Nutrition, Children's Healthcare of Atlanta, Emory University School of Medicine, Atlanta, GA.
Miglena GeorgievaSecond Pediatric Clinic, University Hospital St Marina, Varna, Bulgaria.
Danijela Jojkić-PavkovDepartment of Gastroenterology, Hepatology and Nutrition, Institute for Child and Youth Health Care of Vojvodina, Medical Faculty, University of Novi Sad, Novi Sad, Serbia.
Daina KalninsDepartment of Clinical Dietetics, The Hospital for Sick Children, Toronto, Ontario, Canada.
Brigitte KochaviPediatric Gastroenterology Unit, The Edmond and Lily Safra Children's Hospital, The Haim Sheba Medical Center, Ramat Gan, Israel.
Bart G P KootDepartment of Pediatric Gastroenterology, Academic Medical Centre, Amsterdam, The Netherlands.
Stephanie Van BiervlietPediatric Gastroenterology and Nutrition, Ghent University Hospital, Ghent, Belgium.
Jaroslaw WalkowiakDepartment of Pediatric Gastroenterology & Metabolic Diseases, Poznan University of Medical Sciences, Poznan, Poland.
Michael WilschanskiPediatric Gastroenterology, Hadassah Hebrew University Medical Center, Jerusalem, Israel.
Veronique D MorinvilleDivision of Pediatric Gastroenterology and Nutrition, Montreal Children's Hospital, McGill University Health Centre, Montreal, Quebec, Canada.
Emory University · USUniversity of Iowa Stead Family Children’s Hospital · USCincinnati Children's Hospital Medical Center · USEdmond and Lily Safra Children's Hospital · ILGhent University Hospital · BEHadassah Medical Center · ILHospital for Sick Children · CAInstitute of Public Health of Vojvodina · RSMedical College of Wisconsin · USUniversity Hospital St. Marina · BGUniversity of Novi Sad · RS

Funding

Vector Core-Core 2P30DK054759 · NIDDK · UNIVERSITY OF IOWA · PI Alejandro Antonio Pezzulo · 1998 to 2026
$30.5M
Year 9 Administrative Supplement to INSPPIRE 2U01DK108334 · NIDDK · UNIVERSITY OF IOWA · PI MARK E. LOWE, Aliye Uc · 2015 to 2026
$10.5M
Fatty Acid Defects & Oxidative Stress Modulate Islet Function in Cystic FibrosisR01DK097820 · NIDDK · UNIVERSITY OF IOWA · PI NORRIS, ANDREW W, UC, ALIYE · 2012 to 2016
$1.9M
INSPPIRE TO STUDY ACUTE RECURRENT AND CHRONIC PANCREATITIS IN CHILDRENR21DK096327 · NIDDK · UNIVERSITY OF IOWA · PI UC, ALIYE · 2012 to 2014
$586k
PancreasCHIP - A diagnostic tool for Inheritable Pancreatic DiseaseR43DK105640 · NIDDK · P2D, INC. · PI ABU-EL-HAIJA, MAISAM, ZEMLAN, FRANK · 2015 to 2015
$266k
NIDDK NIH HHS P30 DK054759NIDDK NIH HHS R01 DK097820NIDDK NIH HHS R21 DK096327NIDDK NIH HHS R43 DK105640NIDDK NIH HHS U01 DK108334
6 · The paper itself

Abstract

objectivesWide variations exist in how physicians manage the nutritional aspects of children affected by acute pancreatitis (AP), acute recurrent pancreatitis (ARP), and chronic (CP) pancreatitis. Better consensus for optimal management is needed.

methodsThis consensus statement on nutrition in pediatric pancreatic diseases was developed through a joint ESPGHAN-NASPGHAN working group that performed an evidence-based search of the literature on nutrition in AP, ARP, and CP with a focus on pediatrics. The literature was summarized, quality of evidence reviewed, and expert recommendations developed. The authorship met to discuss the evidence and statements. Voting on recommendations occurred over 2 rounds based on feedback. A consensus of at least 75% was required to approve a recommendation. Areas requiring further research were identified. RESULTS AND DISCUSSION: The literature on nutrition in pediatric pancreatitis is limited. Children with mild AP benefit from starting an early nutritional regimen in the course of the attack. Early nutrition should be attempted in severe AP when possible; enteral nutrition is preferred over parenteral nutrition. Children with ARP are likely to tolerate and benefit from a regular diet. Children with CP need ongoing assessment for growth and nutritional deficiencies, exocrine and endocrine insufficiencies.

conclusionsThis document presents the first authoritative recommendations on nutritional considerations in pediatric pancreatitis. Future research should address the gaps in knowledge particularly relating to optimal nutrition for AP in children, role of diet or dietary supplements on recurrent attacks of pancreatitis and pain episodes, monitoring practices to detect early growth and nutritional deficiencies in CP and identifying risk factors that predispose children to these deficiencies.

Indexed as

DietNutritional SupportAdolescentAntioxidantsChildChild, PreschoolConsensusDiabetes MellitusDietary FatsExocrine Pancreatic InsufficiencyFood, FormulatedHumansInfantInfant, NewbornIntubation, GastrointestinalPancreatitisAntioxidantsDietary Fats

Identifiers

PMID29927872
PMCPMC6020697
OpenAlexW2801904928

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.