Evidence map›Paper›PMID 29935073›Full record

ArticleInternational journal of fertility & sterility2018

Anti-Oxidative and Anti-Apoptotic Effects of Apigenin on Number of Viable and Apoptotic Blastomeres, Zona Pellucida Thickness and Hatching Rate of Mouse Embryos.

Manouchehr Safari, Houman Parsaie, Hamid Reza Sameni, Mohammad Reza Aldaghi, Sam Zarbakhsh

Open access · greenAbstract read
In one paragraph

Article in International journal of fertility & sterility, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Asiaticoside attenuates hyperoxia-induced lung injuryIranian journal of basic medical sciences · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Manouchehr SafariNervous System Stem Cells Research Center, Faculty of Medicine, Semnan University of Medical Sciences, Semnan, Iran.
Houman ParsaieNervous System Stem Cells Research Center, Faculty of Medicine, Semnan University of Medical Sciences, Semnan, Iran.
Hamid Reza SameniNervous System Stem Cells Research Center, Faculty of Medicine, Semnan University of Medical Sciences, Semnan, Iran.
Mohammad Reza AldaghiNervous System Stem Cells Research Center, Faculty of Medicine, Semnan University of Medical Sciences, Semnan, Iran.
Sam ZarbakhshNervous System Stem Cells Research Center, Faculty of Medicine, Semnan University of Medical Sciences, Semnan, Iran. Electronic Address: smzarbakhsh@gmail.com.
Semnan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundApigenin is a plant-derived compound belonging to the flavonoids category and bears protective effects on different cells. The aim of this study was to evaluate the effect of apigenin on the number of viable and apoptotic blastomeres, the zona pellucida (ZP) thickness and hatching rate of pre-implantation mouse embryos exposed to H MATERIALS AND

methodsIn this experimental study, 420 two-cell embryos were randomly divided into six groups: i. Control, ii. Apigenin, iii. H

resultsThe results of viable and apoptotic blastomeres quantity, the ZP thickness, and the percentage of blastocysts and hatched blastocysts were significantly more favorable in the apigenin group, rather than the control group (P<0.05). The results of the apigenin+H

conclusionThe results suggest that apigenin may protect mouse embryos against H

Indexed as

ApigeninApoptosisBlastomeresEmbryonic DevelopmentZona Pellucida

Identifiers

PMID29935073
PMCPMC6018174
OpenAlexW2916863587

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.