Evidence map›Paper›PMID 29950954›Full record

ArticleContrast media & molecular imaging2018

Positron Emission Tomography Imaging of Macrophages in Atherosclerosis with

Sanna Hellberg, Heidi Liljenbäck, Olli Eskola, Veronique Morisson-Iveson, Matthew Morrison, William Trigg, Pekka Saukko, Seppo Ylä-Herttuala, Juhani Knuuti, Antti Saraste and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Contrast media & molecular imaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 34 citations in OpenAlex.

  1. Radiopharmaceuticals and their applications in medicine.Signal transduction and targeted therapy · 2025
    Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Reduced Acquisition Time [Frontiers in medicine · 2022
    Article
  8. Review
  9. Positron Emission Tomography in Atherosclerosis Research.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  10. Review
  11. Dissecting the target leukocyte subpopulations of clinically relevant inflammation radiopharmaceuticals.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  12. Review
  13. Review
  14. Atherosclerosis Immunoimaging by Positron Emission Tomography.Arteriosclerosis, thrombosis, and vascular biology · 2020
    Review
  15. Article
  16. PET imaging of macrophages in cardiovascular diseases.American journal of translational research · 2020
    Review
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Sanna HellbergTurku PET Centre, University of Turku, Kiinamyllynkatu 4-8, 20520 Turku, Finland.ORCID 0000-0003-1791-3693
Heidi LiljenbäckTurku PET Centre, University of Turku, Kiinamyllynkatu 4-8, 20520 Turku, Finland.
Olli EskolaTurku PET Centre, University of Turku, Kiinamyllynkatu 4-8, 20520 Turku, Finland.
Veronique Morisson-IvesonGE Healthcare Ltd., White Lion Road, Amersham, Buckinghamshire HP7 9LL, UK.
Matthew MorrisonGE Healthcare Ltd., White Lion Road, Amersham, Buckinghamshire HP7 9LL, UK.
William TriggGE Healthcare Ltd., White Lion Road, Amersham, Buckinghamshire HP7 9LL, UK.
Pekka SaukkoDepartment of Pathology and Forensic Medicine, University of Turku, Kiinamyllynkatu 10, 20520 Turku, Finland.
Seppo Ylä-HerttualaA.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Neulaniementie 2, 70210 Kuopio, Finland.ORCID 0000-0001-7593-2708
Juhani KnuutiTurku PET Centre, University of Turku, Kiinamyllynkatu 4-8, 20520 Turku, Finland.
Antti SarasteTurku PET Centre, University of Turku, Kiinamyllynkatu 4-8, 20520 Turku, Finland.
Anne RoivainenTurku PET Centre, University of Turku, Kiinamyllynkatu 4-8, 20520 Turku, Finland.ORCID 0000-0002-4006-7977
University of Turku · FIUniversity of Eastern Finland · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intraplaque inflammation plays an important role in the progression of atherosclerosis. The 18 kDa translocator protein (TSPO) expression is upregulated in activated macrophages, representing a potential target to identify inflamed atherosclerotic plaques. We preclinically evaluated

Indexed as

AtherosclerosisMacrophagesPlaque, AtheroscleroticPositron-Emission TomographyAnimalsCarbazolesDisease Models, AnimalImmunohistochemistryMiceMice, KnockoutRadiopharmaceuticalsReceptors, GABAReceptors, LDLBzrp protein, mouseCarbazolesGE-180RadiopharmaceuticalsReceptors, GABAReceptors, LDL

Identifiers

PMID29950954
PMCPMC5987326
OpenAlexW2804059160

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.