Trial reportActa paediatrica (Oslo, Norway : 1992)2019
Low-saturated-fat and low-cholesterol diet does not alter pubertal development and hormonal status in adolescents.
Trial report in Acta paediatrica (Oslo, Norway : 1992), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 6 citations in OpenAlex.
- Longitudinal effect of 20-year infancy-onset dietary intervention on food consumption and nutrient intake: the randomized controlled STRIP study.European journal of clinical nutrition · 2019Trial
- Pubertal Timing Associates With Cardiometabolic Markers During Puberty and in Young Adulthood.Acta paediatrica (Oslo, Norway : 1992) · 2026Article
- Associations of academic performance, sports participation, disordered eating and menstrual cycle irregularities in adolescents: a population-based study.BMJ open sport & exercise medicine · 2026Article
- Weight Gain in Infancy and Childhood Were Associated With Pubertal Development in Boys and Girls.Acta paediatrica (Oslo, Norway : 1992) · 2025Article
- Cryptorchidism and puberty.Frontiers in endocrinology · 2024Review
- Article
- Prepubertal Dietary and Plasma Phospholipid Fatty Acids Related to Puberty Timing: Longitudinal Cohort and Mendelian Randomization Analyses.Nutrients · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 2 institutions in 2 countries.
Funding
Abstract
aimThe aim was to assess the influence of dietary counselling on the pubertal development and hormonal status in healthy adolescents.
methodsWe used a subcohort of 193 healthy boys (52%) and girls (48%) from the Special Turku Coronary Risk Factor Intervention Project. Participants were recruited by nurses at the well-baby clinics in Turku Finland in 1990-1992 and randomised into intervention and control groups. Intervention children received low-saturated fat and low-cholesterol dietary counselling initiated at seven months of age. Participants were examined once a year with Tanner staging, anthropometric measurements and serial reproductive hormones from 10 to 19 years of age. In girls, postmenarcheal hormones were not analysed.
resultsPubertal hormones in boys or girls did not differ between the intervention and control groups. However, we observed slight differences in pubertal progression by Tanner staging and in anthropometric parameters. The intervention boys progressed faster to G4 (p = 0.008), G5 (p = 0.008) and P5 (p = 0.03). The intervention boys were taller than control boys (p = 0.04), while weight and body mass index did not differ.
conclusionDietary intervention did not affect pubertal hormonal status. This finding supports the safety of implemented counselling in respect to puberty.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.