Evidence map›Paper›PMID 29961157›Full record

ReviewCellular and molecular life sciences : CMLS2018

Trans-spliced long non-coding RNA: an emerging regulator of pluripotency.

Chun-Ying Yu, Ching-Yu Chuang, Hung-Chih Kuo

Abstract readReview
In one paragraph

Review in Cellular and molecular life sciences : CMLS, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Chun-Ying YuInstitute of Cellular and Organismic Biology, Academia Sinica, No. 128, Sec. 2, Academia Road, Nankang, Taipei, 11529, Taiwan.
Ching-Yu ChuangGenomics Research Center, Academia Sinica, Taipei, 11529, Taiwan.
Hung-Chih KuoInstitute of Cellular and Organismic Biology, Academia Sinica, No. 128, Sec. 2, Academia Road, Nankang, Taipei, 11529, Taiwan. kuohuch@gate.sinica.edu.tw.

Funding

Academia Sinica (TW) AS-103-TP-B10Academia Sinica (TW) AS-104-TP-B09Ministry of Science and Technology, Taiwan MOST104-0210-01-09-02Ministry of Science and Technology, Taiwan (TW) MOST105-0210-01-13-01Ministry of Science and Technology, Taiwan (TW) MOST106-0210-01-15-02Ministry of Science and Technology, Taiwan (TW) MOST106-2321-B-001-049-MY3National Health Research Institutes (TW) NHRI-EX104-10320SI
6 · The paper itself

Abstract

With dual capacities for unlimited self-renewal and pluripotent differentiation, pluripotent stem cells (PSCs) give rise to many cell types in our body and PSC culture systems provide an unparalleled opportunity to study early human development and disease. Accumulating evidence indicates that the molecular mechanisms underlying pluripotency maintenance in PSCs involve many factors. Among these regulators, recent studies have shown that long non-coding RNAs (lncRNAs) can affect the pluripotency circuitry by cooperating with master pluripotency-associated factors. Additionally, trans-spliced RNAs, which are generated by combining two or more pre-mRNA transcripts to produce a chimeric RNA, have been identified as regulators of various biological processes, including human pluripotency. In this review, we summarize and discuss current knowledge about the roles of lncRNAs, including trans-spliced lncRNAs, in controlling pluripotency.

Indexed as

Embryonic Stem CellsGene Regulatory NetworksHumansInduced Pluripotent Stem CellsRNA, Long NoncodingSignal TransductionTranscription FactorsTrans-SplicingRNA, Long NoncodingTranscription FactorsHuman embryonic stem cellsInduced pluripotent stem cellsLong non-coding RNAsPluripotencyTrans-spliced RNA

Identifiers

PMID29961157
PMCPMC11105688

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.