Evidence mapPaperPMID 29966295Full record

ReviewInternational journal of molecular sciences2018

Regulation of CYP2J2 and EET Levels in Cardiac Disease and Diabetes.

Theresa Aliwarga, Eric A Evangelista, Nona Sotoodehnia, Rozenn N Lemaitre, Rheem A Totah

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 59 citations in OpenAlex.

  1. Article
  2. Impacts of Oxylipins on ischemic stroke: from pathophysiology to clinical phenotypes.Metabolomics : Official journal of the Metabolomic Society · 2025
    Review
  3. Article
  4. Article
  5. INTEDE 2.0: the metabolic roadmap of drugs.Nucleic acids research · 2024
    Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Recent developments inDrug metabolism reviews · 2021
    Article
  17. Review
  18. Gigantol ameliorates CClScientific reports · 2020
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Theresa AliwargaDepartment of Medicinal Chemistry, University of Washington, Seattle, WA 98101, USA. tessa629@uw.edu.
Eric A EvangelistaDepartment of Medicinal Chemistry, University of Washington, Seattle, WA 98101, USA. evangelista.ea@gmail.com.
Nona SotoodehniaCardiovascular Health Research Unit, University of Washington, Seattle, WA 98195, USA. nsotoo@u.washington.edu.
Rozenn N LemaitreCardiovascular Health Research Unit, University of Washington, Seattle, WA 98195, USA. rozenl@uw.edu.
Rheem A TotahDepartment of Medicinal Chemistry, University of Washington, Seattle, WA 98101, USA. rtotah@uw.edu.
University of Washington · US

Funding

DRUG ACTION, METABOLISM AND KINETICST32GM007750 · UNIVERSITY OF WASHINGTON · 1985 to 2005
$3.0M
NCATS NIH HHS TL1 TR000422NHLBI NIH HHS R01 HL128709NHLBI NIH HHS R01 HL130880NIGMS NIH HHS T32 GM007750
6 · The paper itself

Abstract

Cytochrome P450 2J2 (CYP2J2) is a known arachidonic acid (AA) epoxygenase that mediates the formation of four bioactive regioisomers of

Indexed as

AnimalsCardiovascular DiseasesCytochrome P-450 CYP2J2Cytochrome P-450 Enzyme SystemDiabetes MellitusHeart DiseasesHumansHydroxyeicosatetraenoic AcidsHypertensionCYP2J2 protein, humanCytochrome P-450 CYP2J2Cytochrome P-450 Enzyme SystemHydroxyeicosatetraenoic Acidscardiovascular diseaseCYP2J2diabetesepoxyeicosatrienoic acidshypertension

Identifiers

PMID29966295
PMCPMC6073148
OpenAlexW2810629639

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.