Evidence map›Paper›PMID 29968499›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2019

Flow-metabolism uncoupling in patients with asymptomatic unilateral carotid artery stenosis assessed by multi-modal magnetic resonance imaging.

Jens Göttler, Stephan Kaczmarz, Michael Kallmayer, Isabel Wustrow, Hans-Henning Eckstein, Claus Zimmer, Christian Sorg, Christine Preibisch, Fahmeed Hyder

Open access · bronzeAbstract read
In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 40 citations in OpenAlex.

  1. Imaging effective oxygen diffusivity in the human brain with multiparametric magnetic resonance imaging.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2022
    Trial
  2. The stronger one-sided relative hypoperfusion, the more pronounced ipsilateral spatial attentional bias in patients with asymptomatic carotid stenosis.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2020
    Trial
  3. Baseline electrophysiology versus oxidative metabolism as traits of inter-network differences in neurometabolic association.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
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  10. Article
  11. Macro- and microvascular contributions to cerebral structural alterations in patients with asymptomatic carotid artery stenosis.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024
    Article
  12. Validation of a new 3D quantitative BOLD based cerebral oxygen extraction mapping.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024
    Article
  13. Article
  14. Article
  15. Spatiotemporal features of neurovascular (un)coupling with stimulus-induced activity and hypercapnia challenge in cerebral cortex and olfactory bulb.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023
    Article
  16. Article
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  18. Review
  19. Article
  20. Mapping oxidative metabolism in the human brain with calibrated fMRI in health and disease.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Jens GöttlerDepartment of Radiology & Biomedical Imaging, Magnetic Resonance Research Center, Yale University, New Haven, CT, USA.ORCID 0000-0002-5746-2156
Stephan KaczmarzDepartment of Radiology & Biomedical Imaging, Magnetic Resonance Research Center, Yale University, New Haven, CT, USA.ORCID 0000-0001-7694-7012
Michael KallmayerDepartment of Vascular and Endovascular Surgery, Technische Universität München, Klinikum rechts der Isar, Munich, Germany.
Isabel WustrowI. Medizinische Klinik und Poliklinik, Technische Universität München, Klinikum rechts der Isar, Munich, Germany.
Hans-Henning EcksteinDepartment of Vascular and Endovascular Surgery, Technische Universität München, Klinikum rechts der Isar, Munich, Germany.
Claus ZimmerDepartment of Diagnostic and Interventional Neuroradiology, Technische Universität München, Klinikum rechts der Isar, Munich, Germany.
Christian SorgDepartment of Diagnostic and Interventional Neuroradiology, Technische Universität München, Klinikum rechts der Isar, Munich, Germany.
Christine PreibischDepartment of Diagnostic and Interventional Neuroradiology, Technische Universität München, Klinikum rechts der Isar, Munich, Germany.ORCID 0000-0003-4067-1928
Fahmeed HyderDepartment of Radiology & Biomedical Imaging, Magnetic Resonance Research Center, Yale University, New Haven, CT, USA.
TUM Klinikum · DEYale University · US

Funding

NeurophysiologicP30NS052519 · NINDS · YALE UNIVERSITY · PI HYDER, DEWAN SYED FAHMEED · 2007 to 2017
$6.7M
Energetics of Neuronal Populations by fMRIR01MH067528 · NIMH · YALE UNIVERSITY · PI HYDER, DEWAN SYED FAHMEED · 2002 to 2021
$5.9M
MRS validation of computational metabolic modeling of human brain function to determine energetic disruptions underlying fMRI-derived functional connectivity in degenerative or psychiatric disordersR01NS100106 · NINDS · YALE UNIVERSITY · PI HYDER, DEWAN SYED FAHMEED, ROTHMAN, DOUGLAS LYLE · 2017 to 2021
$959k
NIMH NIH HHS R01 MH067528NINDS NIH HHS P30 NS052519NINDS NIH HHS R01 NS100106
6 · The paper itself

Abstract

Oxygen extraction (OEF), oxidative metabolism (CMRO

Indexed as

Cerebrovascular CirculationHomeostasisBrainCarotid StenosisCase-Control StudiesFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedOxygenOxygenarterial spin labelingCarotid stenosiscerebral blood flowcerebral metabolic rate of oxygen consumptionmulti-parametric quantitative blood oxygenation level dependent imagingperfusion

Identifiers

PMID29968499
PMCPMC6827123
OpenAlexW2811143824

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.