Evidence map›Paper›PMID 29969193›Full record

ReviewJournal of magnetic resonance imaging : JMRI2018

Applications of PET-MRI in musculoskeletal disease.

Feliks Kogan, Stephen M Broski, Daehyun Yoon, Garry E Gold

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Journal of magnetic resonance imaging : JMRI, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05801848 (Diagnosis of Bone Metabolism in Patients With Inexplicable Lower Back Pain), which is not on this map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05801848 active not recruitingnot on this mapstarted 2023, after this paper: background citation

Diagnosis of Bone Metabolism in Patients With Inexplicable Lower Back Pain

TypeobservationalSponsorRigshospitalet, DenmarkRan2023 to 2026Enrolled50ConditionsLower Back Pain ChronicArms[18F]NaF PET/CT scan
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 56 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Role of Total Body PET/CT in Inflammatory Disorders.Seminars in nuclear medicine · 2025
    Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Impact of theJournal of clinical medicine · 2021
    Article
  16. Assessment of quantitative [Osteoarthritis and cartilage · 2021
    Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Feliks KoganDepartment of Radiology, Stanford University, Stanford, California, USA.
Stephen M BroskiDepartment of Radiology, Mayo Clinic, Rochester, Minnesota, USA.
Daehyun YoonDepartment of Radiology, Stanford University, Stanford, California, USA.
Garry E GoldDepartment of Radiology, Stanford University, Stanford, California, USA.
Stanford University · USMayo Clinic · US

Funding

Rapid MRI for Evaluation of OsteoarthritisR01EB002524 · NIBIB · STANFORD UNIVERSITY · PI Akshay Chaudhari, Garry E Gold · 2003 to 2026
$10.1M
Advanced MR Imaging of Early OsteoarthritisK24AR062068 · NIAMS · STANFORD UNIVERSITY · PI GOLD, GARRY E · 2012 to 2022
$1.7M
Quantitative Assessment of Early Metabolic and Biochemical Changes in OsteoarthritisK99EB022634 · NIBIB · STANFORD UNIVERSITY · PI KOGAN, FELIKS · 2017 to 2018
$184k
NIAMS NIH HHS K24 AR062068NIBIB NIH HHS K99 EB022634NIBIB NIH HHS R01 EB002524
6 · The paper itself

Abstract

New integrated PET-MRI systems potentially provide a complete imaging modality for diagnosis and evaluation of musculoskeletal disease. MRI is able to provide excellent high-resolution morphologic information with multiple contrast mechanisms that has made it the imaging modality of choice in evaluation of many musculoskeletal disorders. PET offers incomparable abilities to provide quantitative information about molecular and physiologic changes that often precede structural and biochemical changes. In combination, hybrid PET-MRI can enhance imaging of musculoskeletal disorders through early detection of disease as well as improved diagnostic sensitivity and specificity. The purpose of this article is to review emerging applications of PET-MRI in musculoskeletal disease. Both clinical applications of malignant musculoskeletal disease as well as new opportunities to incorporate the molecular capabilities of nuclear imaging into studies of nononcologic musculoskeletal disease are discussed. Lastly, we discuss some of the technical considerations and challenges of PET-MRI as they specifically relate to musculoskeletal disease. LEVEL OF EVIDENCE: 5 TECHNICAL EFFICACY: Stage 3 J. Magn. Reson. Imaging 2018;48:27-47.

Indexed as

Magnetic Resonance ImagingPositron-Emission TomographyAdultArthritis, RheumatoidBone and BonesBone DiseasesHumansMetalsMultimodal ImagingMultiple MyelomaMuscle, SkeletalMusculoskeletal DiseasesNeoplasm MetastasisOsteoarthritisPainPrognosisMetalsbonejointmolecular imagingmusculoskeletal diseasePET-MRI

Identifiers

PMID29969193
PMCPMC6032526
OpenAlexW2810567601

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.