Evidence mapPaperPMID 29974262Full record

ReviewCurrent hypertension reports2018

Arterial Stiffness in Hypertension: an Update.

Korshie Dumor, Michael Shoemaker-Moyle, Ravi Nistala, Adam Whaley-Connell

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current hypertension reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 1 pooled it
8.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 1 synthesis or guideline pooled it, 108 citations in OpenAlex.

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  9. Acute vascular and cardiac effects of lenvatinib in mice.Cardio-oncology (London, England) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Korshie DumorDivision of Nephrology and Hypertension, Department of Medicine, University of Missouri School of Medicine, Columbia, MO, USA. Dumork@health.missouri.edu.
Michael Shoemaker-MoyleDivision of Nephrology and Hypertension, Department of Medicine, University of Missouri School of Medicine, Columbia, MO, USA.
Ravi NistalaDivision of Nephrology and Hypertension, Department of Medicine, University of Missouri School of Medicine, Columbia, MO, USA.
Adam Whaley-ConnellDivision of Nephrology and Hypertension, Department of Medicine, University of Missouri School of Medicine, Columbia, MO, USA.
University of Missouri · USHarry S. Truman Memorial Veterans' Hospital · US

Funding

BLRD VA I01 BX003391
6 · The paper itself

Abstract

purpose of reviewTo update and review novel insights into the mechanisms, measurements, and therapeutic approaches to arterial stiffness. RECENT

findingsArterial (e.g., vascular) stiffness has been shown over time to prognosticate for cardiovascular and kidney outcomes. In this context, there has been increased interest behind the mechanisms that drive arterial stiffness beyond aging and interest in how to apply newer technologies in measurement of arterial stiffness. Pulse wave velocity has been the gold standard for measurement but industry has been innovating to improve measurement with use of single-point PWV as well as pharmacologic approaches with anti-hypertensives and oral hypoglycemic agents. Emerging data on the role of the mineralocorticoid receptor, the endothelial sodium channel (EnNaC), and uric acid in arterial stiffness are promising a number of potential therapies. Newer techniques of measuring PWV for arterial stiffness and novel therapies may soon lead to better outcomes from hypertension complications.

Indexed as

HypertensionVascular StiffnessAntihypertensive AgentsHumansPulse Wave AnalysisTherapies, InvestigationalUric AcidAntihypertensive AgentsUric AcidArterial stiffnessEndothelial ENaCHypertensionMineralocorticoid receptorPWVRAAS

Identifiers

PMID29974262
OpenAlexW2809990798

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.