Evidence map›Paper›PMID 29974800›Full record

ArticleJournal of biological rhythms2018

Functional Significance of the Excitatory Effects of GABA in the Suprachiasmatic Nucleus.

John K McNeill, James C Walton, H Elliott Albers

Open access · greenAbstract read
In one paragraph

Article in Journal of biological rhythms, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Systematic review of drugs that modify the circadian system's phase-shifting responses to light exposure.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022
    Pooled it
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Observational
  8. Role of the cation-chloride-cotransporters in the circadian system.Asian journal of pharmaceutical sciences · 2021
    Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

John K McNeillNeuroscience Institute and Center for Behavioral Neuroscience, Georgia State University, Atlanta, GA, USA.
James C WaltonNeuroscience Institute and Center for Behavioral Neuroscience, Georgia State University, Atlanta, GA, USA.ORCID 0000-0002-3049-1029
H Elliott AlbersNeuroscience Institute and Center for Behavioral Neuroscience, Georgia State University, Atlanta, GA, USA.ORCID 0000-0001-7491-3978
Georgia State University · US

Funding

Communication within the Suprachiasmatic Neural Circadian NetworkR01NS078220 · NINDS · GEORGIA STATE UNIVERSITY · PI ALBERS, H. ELLIOTT · 2012 to 2016
$1.6M
Neurobiology of Social BehaviorR01MH062641 · NIMH · GEORGIA STATE UNIVERSITY · PI ALBERS, ELLIOTT H · 2001 to 2005
$1.3M
The roles of GABA receptor subunits in circadian rhythms in GABA responsiveness in the suprachiasmatic nucleusF32NS092545 · NINDS · GEORGIA STATE UNIVERSITY · PI WALTON, JAMES C. · 2015 to 2017
$168k
NIMH NIH HHS R01 MH062641NINDS NIH HHS F32 NS092545NINDS NIH HHS R01 NS078220
6 · The paper itself

Abstract

Over 90% of neurons within the suprachiasmatic nucleus (SCN) express γ-aminobutyric acid (GABA). Although GABA is primarily an inhibitory neurotransmitter, in vitro studies suggest that the activation of GABA

Indexed as

PhotoperiodAnimalsBumetanideCircadian RhythmCricetinaeDarknessgamma-Aminobutyric AcidMaleMesocricetusReceptors, GABASolute Carrier Family 12, Member 2Suprachiasmatic NucleusBumetanidegamma-Aminobutyric AcidReceptors, GABASolute Carrier Family 12, Member 2chloridecircadianentrainmentGABAGABAA receptorsNKCC1phase shifting

Identifiers

PMID29974800
PMCPMC6419757
OpenAlexW2875686737

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.