ArticlePediatrics2018
Clinical Implications of the Revised AAP Pediatric Hypertension Guidelines.
Article in Pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04752293 (Pediatric Hypertension and the Renin-Angiotensin SystEm), which is not on this map. Cited by 33 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Pediatric Hypertension and the Renin-Angiotensin SystEm (PHRASE): The Role of Angiotensin-(1-7) in Hypertension and Hypertension-Induced Heart and Kidney Damage
Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it, 79 citations in OpenAlex.
- Hypertension in Children and Adolescents: A Position Statement From a Panel of Multidisciplinary Experts Coordinated by the French Society of Hypertension.Frontiers in pediatrics · 2021Pooled it
- High Blood Pressure in Children Aged 3 to 12 Years Old With Overweight or Obesity.Childhood obesity (Print) · 2024Trial
- The prevention of adult cardiovascular disease must begin in childhood: evidence and imperative.Nature reviews. Cardiology · 2026Review
- Leveraging adolescents as health advocates: Evaluating hypertension education's impact on knowledge retention & family health compliance.The Indian journal of medical research · 2025Article
- Rising pressure to understand the risks of hypertension in children with narcolepsy type 1.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025Article
- Association between systemic inflammation markers and blood pressure among children and adolescents: National Health and Nutrition Examination Survey.Pediatric research · 2025Article
- The Study of the Epidemiology of Pediatric Hypertension Registry (SUPERHERO): rationale and methods.American journal of epidemiology · 2024Article
- Pediatric High Blood Pressure Recognition Associated With Electronic Decision Support: A Cohort Analysis.Hypertension (Dallas, Tex. : 1979) · 2024Article
- Comparative analysis of adolescent hypertension definitions for predicting early adulthood carotid artery intima-media thickness: Tehran lipid and glucose study.Clinical and experimental pediatrics · 2024Article
- The ongoing impact of obesity on childhood hypertension.Pediatric nephrology (Berlin, Germany) · 2024Review
- Blood Pressure in Children in the 21st Century: What Do We Know and Where Do We Go From Here?Hypertension (Dallas, Tex. : 1979) · 2023Review
- Prevalence of Hypertension among Children Based on the New American Academy of Pediatrics Clinical Practice Guidelines.Iranian journal of public health · 2023Article
- Impact of the 2017 AAP clinical guideline on the prevalence of high blood pressure among adolescents in Lagos, Nigeria.Frontiers in pediatrics · 2023Article
- High blood pressure pattern amongst adolescents in Lagos, South West Nigeria.The Pan African medical journal · 2023Article
- Ambulatory Blood Pressure Monitoring in Children and Adolescents: 2022 Update: A Scientific Statement From the American Heart Association.Hypertension (Dallas, Tex. : 1979) · 2022Review
- Re-evaluating hypertension in children according to different guidelines: a single-center study.Hypertension research : official journal of the Japanese Society of Hypertension · 2022Article
- Borderline and Hypertension.Hypertension (Dallas, Tex. : 1979) · 2022Article
- Prevalence Implications of the 2017 American Academy of Pediatrics Hypertension Guideline and Associations with Adult Hypertension.The Journal of pediatrics · 2022Article
- Prevalence of arterial hypertension among Ukrainian students: the comparison of European and American guidelines.Pediatric endocrinology, diabetes, and metabolism · 2022Article
- Diagnosis of hypertension: Ambulatory pediatric American Heart Association/European Society of Hypertension versus blood pressure load thresholds.Journal of clinical hypertension (Greenwich, Conn.) · 2021Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
BACKGROUND AND
objectivesNew pediatric hypertension definitions were recently published in a clinical practice guideline (CPG). We evaluated the impact of the CPG, compared with the previous guideline ("Fourth Report on the Diagnosis, Evaluation, and Treatment of High Blood Pressure in Children and Adolescents"), on the prevalence of hypertension and associations with target organ damage (TOD) in high-risk youth.
methodsParticipants (10-18 years old) undergoing an evaluation of the cardiovascular effects of obesity and type 2 diabetes mellitus in youth were studied. Blood pressure was categorized according to the 2 guidelines as normal, elevated, and hypertension (stages 1 and 2). Measures of TOD (carotid artery intima-media thickness, pulse wave velocity, left ventricular mass, and diastolic function) were obtained. Associations between blood pressure categories and TOD and the sensitivity of hypertension classification in identifying TOD were evaluated.
resultsData were available for 364 participants (65% female sex; 15.1 ± 2.1 years of age). Hypertension was identified in 8% and 13% as defined in the Fourth Report and CPG, respectively (
conclusionsIncorporation of the CPG increased the prevalence of pediatric hypertension in a population of high-risk youth and improved the sensitivity of TOD identification in hypertensive participants.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.