Evidence map›Paper›PMID 29991877›Full record

ArticleWorld journal of gastroenterology2018

Gastric cancer in Alaska Native people: A cancer health disparity.

Holly A Martinson, Nancy J Shelby, Steven R Alberts, Matthew J Olnes

Registry-linked trialOpen access · hybridAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of gastroenterology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03629587 (Helicobacter Pylori and it's Hematological Impact), which is not on this map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03629587 completednot on this map

Helicobacter Pylori and it's Hematological Impact

TypeobservationalSponsorAssiut UniversityRan2016 to 2018Enrolled100ConditionsH Pylori Infection
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Cancer Progress and Priorities: Gastric Cancer.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2023
    Article
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  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Holly A MartinsonWWAMI School of Medical Education, University of Alaska Anchorage, Anchorage, AK 99508, United States. hamartinson@alaska.edu.
Nancy J ShelbyWWAMI School of Medical Education, University of Alaska Anchorage, Anchorage, AK 99508, United States.
Steven R AlbertsDepartment of Oncology, Mayo Clinic Cancer Center, Rochester, MN 55905, United States.
Matthew J OlnesHematology and Medical Oncology Department, Alaska Native Medical Center, Anchorage, AK 99508, United States.
Mayo Clinic · USAlaska Native Medical Center · US

Funding

The Administrative CoreP20GM103395 · NIGMS · UNIVERSITY OF ALASKA FAIRBANKS · PI BRIAN M BARNES · 2012 to 2026
$66.1M
NIGMS NIH HHS P20 GM103395
6 · The paper itself

Abstract

aimTo evaluate recent trends in gastric cancer incidence, response to treatment, and overall survival among Alaska Native (AN) people.

methodsA retrospective analysis of the Alaska Native Medical Center patient database was performed. Patient history, clinical, pathological, response to treatment and patient outcomes were collected from one-hundred and thirty-two AN gastric cancer patients. The Surveillance, Epidemiology and End Result database 18 was used to collect comparison United States non-Hispanic White (NHW) and AN gastric cancer patient data between 2006-2014.

resultsAN gastric cancer patients have a higher incidence rate, a poorer overall survival, and are diagnosed at a significantly younger age compared to NHW patients. AN patients differ from NHW patients in greater prevalence of non-cardia, diffuse subtype, and signet ring cell carcinomas. AN females were more likely to be diagnosed with later stage cancer, stage IV, compared to AN males. Diminished overall survival was observed among AN patients with increasing stage, O+ blood type, < 15 lymph nodes examined at resection, and no treatment. This study is the first report detailing the clinicopathologic features of gastric cancer in AN people with outcome data.

conclusionOur findings confirm the importance of early detection, treatment, and surgical resection for optimizing AN patient outcomes. Further research on early detection markers are warranted.

Indexed as

Health Status DisparitiesAdultAgedAged, 80 and overAlaska NativesCarcinoma, Signet Ring CellEarly Detection of CancerFemaleHelicobacter pyloriHumansIncidenceLymph NodesMaleMiddle AgedRetrospective StudiesSEER ProgramAlaska NativeGastric cancerGenderHealth disparitiesHelicobacter pylori

Identifiers

PMID29991877
PMCPMC6034149
OpenAlexW2835505861

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.