Evidence map›Paper›PMID 29999552›Full record

ReviewCell proliferation2018

Regulation and functions of MicroRNA-149 in human cancers.

Yingru Zhi, Hao Zhou, Abudoureyimu Mubalake, Ying Chen, Bei Zhang, Kai Zhang, Xiaoyuan Chu, Rui Wang

Open access · bronzeAbstract readReview
In one paragraph

Review in Cell proliferation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yingru ZhiDepartment of Medical Oncology, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, China.ORCID http://orcid.org/0000-0002-9389-6058
Hao ZhouNanjing Medical University, Nanjing, China.
Abudoureyimu MubalakeDepartment of Medical Oncology, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, China.
Ying ChenDepartment of Medical Oncology, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, China.
Bei ZhangNanjing Medical University, Nanjing, China.
Kai ZhangDepartment of Medical Oncology, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, China.
Xiaoyuan ChuDepartment of Medical Oncology, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, China.
Rui WangDepartment of Medical Oncology, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, China.
Nanjing General Hospital of Nanjing Military Command · CNNanjing Medical University · CN

Funding

Excellent Youth Foundation of Jiangsu Province, China BK20140032National Natural Science Foundation of China 81472266National Natural Science Foundation of China 81772996
6 · The paper itself

Abstract

MicroRNAs are small non-coding RNAs that play critical roles in the regulatory mechanisms involving cell differentiation, proliferation, apoptosis and tumorigenesis. Recent research efforts have been conducted to apply these discoveries into clinical functions, including the early diagnosis and therapeutic outcome of patients with cancer. Previous studies have shown that microRNA-149 (miR-149) is dysregulated in various human cancers and exerts its effects on tumorigenesis and tumour progression. In this review, we summarized the potential roles of miR-149 dysregulation and its target genes during tumorigenesis and clinical treatment of human cancers.

Indexed as

ApoptosisCarcinogenesisCell DifferentiationCell ProliferationHumansMicroRNAsNeoplasmsMicroRNAsMIRN149 microRNA, humancancerchemotherapydiagnosisdysregulationmiR-149prognosis

Identifiers

PMID29999552
PMCPMC6528861
OpenAlexW2853842868

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.