Trial reportNutrients2018
SunGold Kiwifruit Supplementation of Individuals with Prediabetes Alters Gut Microbiota and Improves Vitamin C Status, Anthropometric and Clinical Markers.
Trial report in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 48 citations in OpenAlex.
- Pooled it
- Kiwifruit and Kiwifruit Extracts for Treatment of Constipation: A Systematic Review and Meta-Analysis.Canadian journal of gastroenterology & hepatology · 2022Pooled it
- Discovery of urinary biomarkers of kiwifruit intake in a randomized intervention study.Nutrition journal · 2025Trial
- SunGold Kiwifruit and Psychological Health (GoKiPH): A Randomised Controlled Crossover Trial.Nutrients · 2025Trial
- Effects of Green and Gold Kiwifruit Varieties on Antioxidant Neuroprotective Potential in Pigs as a Model for Human Adults.Nutrients · 2024Article
- The Development and Evaluation of a Literature-Based Dietary Index for Gut Microbiota.Nutrients · 2024Review
- A Proactive Intervention Study in Metabolic Syndrome High-Risk Populations Using Phenome-Based Actionable P4 Medicine Strategy.Phenomics (Cham, Switzerland) · 2024Article
- Effect of Processing on Reduction in Chiral Pesticide Hexaconazole for Kiwifruit Juice.Molecules (Basel, Switzerland) · 2023Article
- Vitamin C Plasma Levels Associated with Inflammatory Biomarkers, CRP and RDW: Results from the NHANES 2003-2006 Surveys.Nutrients · 2022Article
- Vaccines, Microbiota and Immunonutrition: Food for Thought.Vaccines · 2022Review
- The Gut Microbiome Is Associated with Circulating Dietary Biomarkers of Fruit and Vegetable Intake in a Multiethnic Cohort.Journal of the Academy of Nutrition and Dietetics · 2022Article
- Insufficient Vitamin C Levels among Adults in the United States: Results from the NHANES Surveys, 2003-2006.Nutrients · 2021Article
- Effects of Oral Vitamin C Supplementation on Liver Health and Associated Parameters in Patients With Non-Alcoholic Fatty Liver Disease: A Randomized Clinical Trial.Frontiers in nutrition · 2021Article
- Plant polyphenols effect on gut microbiota: Recent advancements in clinical trials.EXCLI journal · 2021Article
- Does Gut-Microbiome Interaction Protect against Obesity and Obesity-Associated Metabolic Disorders?Microorganisms · 2020Review
- Article
- A P4 Medicine Perspective of Gut Microbiota and Prediabetes: Systems Analysis and Personalized Intervention.Journal of translational internal medicine · 2020Article
- Vitamin C Deficiency and the Risk of Osteoporosis in Patients with an Inflammatory Bowel Disease.Nutrients · 2020Review
- Review
- Early Nutrition and Risk of Type 1 Diabetes: The Role of Gut Microbiota.Frontiers in nutrition · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Kiwifruit are a nutrient dense food and an excellent source of vitamin C. Supplementation of the diet with kiwifruit enhances plasma vitamin C status and epidemiological studies have shown an association between vitamin C status and reduced insulin resistance and improved blood glucose control. In vitro experiments suggest that eating kiwifruit might induce changes to microbiota composition and function; however, human studies to confirm these findings are lacking. The aim of this study was to investigate the effect of consuming two SunGold kiwifruit per day over 12 weeks on vitamin C status, clinical and anthropometric measures and faecal microbiota composition in people with prediabetes. This pilot intervention trial compared baseline measurements with those following the intervention. Participants completed a physical activity questionnaire and a three-day estimated food diary at baseline and on completion of the trial. Venous blood samples were collected at each study visit (baseline, 6, 12 weeks) for determination of glycaemic indices, plasma vitamin C concentrations, hormones, lipid profiles and high-sensitivity C-reactive protein. Participants provided a faecal sample at each study visit. DNA was extracted from the faecal samples and a region of the 16S ribosomal RNA gene was amplified and sequenced to determine faecal microbiota composition. When week 12 measures were compared to baseline, results showed a significant increase in plasma vitamin C (14 µmol/L,
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.