Evidence map›Paper›PMID 30002678›Full record

ArticleInternational journal of endocrinology2018

The Role of Uron and Chlorobenzene Derivatives, as Potential Endocrine Disrupting Compounds, in the Secretion of ACTH and PRL.

Krisztian Sepp, Anna M Laszlo, Zsolt Molnar, Andrea Serester, Tunde Alapi, Marta Galfi, Zsuzsanna Valkusz, Marianna Radacs

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of endocrinology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Krisztian SeppFirst Department of Medicine, Faculty of Medicine, University of Szeged, Szeged, Hungary.ORCID 0000-0001-9400-5213
Anna M LaszloDepartment of Biometrics and Agricultural Informatics, Faculty of Horticultural Science, Szent István University, Budapest, Hungary.
Zsolt MolnarDepartment of Environmental Biology and Education, Institute of Environmental and Technological Sciences, Juhász Gyula Faculty of Education, University of Szeged, Szeged, Hungary.
Andrea SeresterDepartment of Environmental Biology and Education, Institute of Environmental and Technological Sciences, Juhász Gyula Faculty of Education, University of Szeged, Szeged, Hungary.
Tunde AlapiDepartment of Inorganic and Analytical Chemistry, Faculty of Science and Informatics, University of Szeged, Szeged, Hungary.
Marta GalfiDepartment of Environmental Biology and Education, Institute of Environmental and Technological Sciences, Juhász Gyula Faculty of Education, University of Szeged, Szeged, Hungary.
Zsuzsanna ValkuszFirst Department of Medicine, Faculty of Medicine, University of Szeged, Szeged, Hungary.
Marianna RadacsDepartment of Environmental Biology and Education, Institute of Environmental and Technological Sciences, Juhász Gyula Faculty of Education, University of Szeged, Szeged, Hungary.
University of Szeged · HUMagyar Agrár- és Élettudományi Egyetem · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Uron herbicides polluting the environment represent a serious concern for environmental health and may be regarded as endocrine-disrupting compounds (EDCs), which influence the regulation of human homeostasis. We aimed to investigate the effect of EDC urons (phenuron: PU, monuron: MU, and diuron: DU) and chlorobenzenes on the basal release of the adrenocorticotropic hormone (ACTH), which is a part of the adenohypophysis-adrenocortical axis. Hormone secretion in the presence of EDC was studied in two cell types: normal adenohypophysis cells (AdH) and cells of prolactinomas (PRLOMA). PRLOMA was induced in female Wistar rats by subcutaneously injecting them with estrone acetate for 6 months. AdH and PRLOMA were separated from treated and untreated experimental animals, dissociated enzymatically and mechanically in order to create monolayer cell cultures, which served as an experimental

Identifiers

PMID30002678
PMCPMC5996407
OpenAlexW2807057423

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.