Evidence map›Paper›PMID 30008018›Full record

ArticleJournal of molecular medicine (Berlin, Germany)2018

Plasma microRNAs as biomarkers for Lamin A/C-related dilated cardiomyopathy.

Rocío Toro, Sara Blasco-Turrión, Francisco José Morales-Ponce, Pablo Gonzalez, Pablo Martínez-Camblor, Amador López-Granados, Ramon Brugada, Oscar Campuzano, Alexandra Pérez-Serra, Felix Rosa Longobardo and 3 more

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of molecular medicine (Berlin, Germany), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Role of miRNA in Cardiovascular Diseases in Children-Systematic Review.International journal of molecular sciences · 2024
    Pooled it
  3. Article
  4. Diagnostic Value of Let-7a-5p in Essential Hypertension.Journal of clinical hypertension (Greenwich, Conn.) · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Circulating circRNA as biomarkers for dilated cardiomyopathy etiology.Journal of molecular medicine (Berlin, Germany) · 2021
    Article
  10. Review
  11. Article
  12. Article
  13. Malignant Arrhythmogenic Role Associated withJournal of personalized medicine · 2021
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 3 countries.

Rocío ToroMedicine Department, School of Medicine, Institute of Research and Innovation in Biomedical Sciences (INiBICA), University of Cádiz, Cádiz, Spain. rocio.toro@uca.es.
Sara Blasco-TurriónCardiology Department, Institute of Research and Innovation in Biomedical Sciences (INiBICA), Puerto Real University Hospital, Cádiz, Spain.
Francisco José Morales-PonceCardiology Department, Institute of Research and Innovation in Biomedical Sciences (INiBICA), Puerto Real University Hospital, Cádiz, Spain.
Pablo GonzalezCardiology Department, Institute of Research and Innovation in Biomedical Sciences (INiBICA), Puerto Real University Hospital, Cádiz, Spain.
Pablo Martínez-CamblorGeisel School of Medicine, Dartmouth College, Hanover, NH, USA.
Amador López-GranadosCardiology Department, Reina Sofía University Hospital, Córdoba, Spain.
Ramon BrugadaCardiovascular Genetics Center, University of Girona-IDIBGI, Girona, Spain.
Oscar CampuzanoCardiovascular Genetics Center, University of Girona-IDIBGI, Girona, Spain.
Alexandra Pérez-SerraCardiovascular Genetics Center, University of Girona-IDIBGI, Girona, Spain.
Felix Rosa LongobardoMedicine Department, School of Medicine, Institute of Research and Innovation in Biomedical Sciences (INiBICA), University of Cádiz, Cádiz, Spain.
Alipio MangasMedicine Department, School of Medicine, Institute of Research and Innovation in Biomedical Sciences (INiBICA), University of Cádiz, Cádiz, Spain.
Vicenta Llorente-CortesCIBER Cardiovascular, Institute of Health Carlos III, Madrid, Spain.
David de Gonzalo-CalvoCIBER Cardiovascular, Institute of Health Carlos III, Madrid, Spain. david.degonzalo@gmail.com.ORCID 0000-0003-2240-3532
Biomedical Research and Innovation Institute of Cadiz · ESUniversidad de Cádiz · ESUniversitat de Girona · ESConsejo Superior de Investigaciones Científicas · ESDartmouth College · USHospital Universitario Reina Sofía · ESInstituto de Salud Carlos III · ES

Funding

Fundació Marató TV3 201521 1Fundación Pública Andaluza Progreso y Salud PI-0011/2014Instituto de Salud Carlos III CB16/11/00403Instituto de Salud Carlos III PI-0011/2014Ministerio de Economía y Competitividad IJCI-2016-29393
6 · The paper itself

Abstract

Lamin A/C gene (LMNA)-related familial dilated cardiomyopathy (fDCM) is an aggressive heart disease that often leads to transplantation and sudden death. The aim of our study was to evaluate the circulating microRNA (miRNA) profiles of patients with LMNA pathogenic mutations. The study population (N = 75) included (i) patients with pathogenic LMNA mutations responsible for fDCM (LMNA

Indexed as

Circulating MicroRNAAdultAllelesAmino Acid SubstitutionBiomarkersCardiomyopathy, DilatedComputational BiologyEchocardiographyFemaleGene Expression ProfilingGenetic Predisposition to DiseaseGenotypeHeart Function TestsHumansLamin Type AMaleBiomarkersCirculating MicroRNALamin Type AMicroRNAsBiomarkersCirculating microRNAsDilated cardiomyopathyLamin A/C (LMNA)

Identifiers

PMID30008018
OpenAlexW2884632796

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.