Evidence mapPaperPMID 30008606Full record

ArticleInternational journal of medical sciences2018

Anti-inflammation and Anti-Cancer Activity of Ethanol Extract of Antarctic Freshwater Microalga,

Sung-Suk Suh, Ju-Mi Hong, Eun Jae Kim, Seung Won Jung, Sun-Mi Kim, Jung Eun Kim, Il-Chan Kim, Sanghee Kim

Open access · goldAbstract read
In one paragraph

Article in International journal of medical sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.

  1. Pooled it
  2. Anticancer Activity of Benzomalvin Derivatives Isolated fromJournal of microbiology and biotechnology · 2025
    Article
  3. Article
  4. Microalgae: revolutionizing skin repair and enhancement.Biotechnology reports (Amsterdam, Netherlands) · 2025
    Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Arctic Sea Ice MicroalgaMarine drugs · 2023
    Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Anti-Inflammatory Effects of Antarctic LichenBioMed research international · 2021
    Article
  15. Article
  16. Network Pharmacology Identifies the Mechanisms of Action of TaohongSiwu Decoction Against Essential Hypertension.Medical science monitor : international medical journal of experimental and clinical research · 2020
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Sung-Suk SuhDepartment of Bioscience, Mokpo National University, Muan 58554, Republic of Korea.
Ju-Mi HongDepartment of Polar Life Sciences, Korea Polar Research Institute, Incheon 21990, Republic of Korea.
Eun Jae KimDepartment of Polar Life Sciences, Korea Polar Research Institute, Incheon 21990, Republic of Korea.
Seung Won JungSouth Sea Environment Research Department, Korea Institute of Ocean Science and Technology, Geoje, 656-830, Republic of Korea.
Sun-Mi KimDepartment of Polar Life Sciences, Korea Polar Research Institute, Incheon 21990, Republic of Korea.
Jung Eun KimDepartment of Polar Life Sciences, Korea Polar Research Institute, Incheon 21990, Republic of Korea.
Il-Chan KimDepartment of Polar Life Sciences, Korea Polar Research Institute, Incheon 21990, Republic of Korea.
Sanghee KimDepartment of Polar Life Sciences, Korea Polar Research Institute, Incheon 21990, Republic of Korea.
Korea Polar Research Institute · KRKorea University of Science and Technology · KRKorea Institute of Ocean Science and Technology · KRMokpo National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammation mediated by the innate immune system is an organism's protective mechanism against infectious environmental risk factors. It is also a driver of the pathogeneses of various human diseases, including cancer development and progression. Microalgae are increasingly being focused on as sources of bioactive molecules with therapeutic potential against various diseases. Furthermore, the antioxidant, anti-inflammatory, and anticancer potentials of microalgae and their secondary metabolites have been widely reported. However, the underlying mechanisms remain to be elucidated. Therefore, in this study, we investigated the molecular mechanisms underlying the anti-inflammatory and anticancer activities of the ethanol extract of the Antarctic freshwater microalga

Indexed as

Antarctic RegionsAntineoplastic AgentsColonic NeoplasmsCyclooxygenase 2EthanolFresh WaterHumansInflammationLipopolysaccharidesMacrophagesMicroalgaeNitric OxideNitric Oxide Synthase Type IIPlant ExtractsTumor Necrosis Factor-alphaAntineoplastic AgentsCyclooxygenase 2EthanolLipopolysaccharidesNitric OxideNitric Oxide Synthase Type IIPlant ExtractsTumor Necrosis Factor-alphacancerHCT116InflammationMicractinium sp.proinflammatory cytokines

Identifiers

PMID30008606
PMCPMC6036089
OpenAlexW2808085241

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.