Evidence map›Paper›PMID 30009201›Full record

ArticleAnnals of clinical and translational neurology2018

Association of severity between carotid and intracranial artery atherosclerosis.

Yilan Xu, Dongye Li, Chun Yuan, Zechen Zhou, Le He, Rui Li, Yuanyuan Cui, Qing Li, Zhuozhao Zheng, Xihai Zhao

Open access · goldAbstract read
In one paragraph

Article in Annals of clinical and translational neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 15 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 2 countries.

Yilan XuDepartment of Radiology Beijing Tsinghua Changgung Hospital School of Clinical Medicine Tsinghua University Beijing China.
Dongye LiCenter for Biomedical Imaging Research Department of Biomedical Engineering Tsinghua University School of Medicine Beijing China.
Chun YuanCenter for Biomedical Imaging Research Department of Biomedical Engineering Tsinghua University School of Medicine Beijing China.
Zechen ZhouPhilips Research North America Cambridge Massachusetts.
Le HeCenter for Biomedical Imaging Research Department of Biomedical Engineering Tsinghua University School of Medicine Beijing China.
Rui LiCenter for Biomedical Imaging Research Department of Biomedical Engineering Tsinghua University School of Medicine Beijing China.
Yuanyuan CuiDepartment of Radiology PLA General Hospital Beijing China.
Qing LiDepartment of Neurology People's Hospital of Xinjiang Vygur Autonomous Region Urumqi China.
Zhuozhao ZhengDepartment of Radiology Beijing Tsinghua Changgung Hospital School of Clinical Medicine Tsinghua University Beijing China.
Xihai ZhaoCenter for Biomedical Imaging Research Department of Biomedical Engineering Tsinghua University School of Medicine Beijing China.
Tsinghua University · CNBeijing Tsinghua Chang Gung Hospital · CNCapital Medical University · CNChinese PLA General Hospital · CNPeople's Hospital of Xinjiang Uygur Autonomous Region · CNPhilips (United States) · USUniversity of Washington · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study sought to investigate the relationship of atherosclerosis between intracranial and extracranial carotid arteries using three-dimensional multicontrast magnetic resonance (MR) vessel wall imaging.

methodsPatients with recent cerebrovascular symptoms in anterior circulation were recruited and underwent MR vessel wall imaging for intracranial and extracranial carotid arteries. The plaque burden, including maximum wall thickness (Max WT) and stenosis, and presence of intraplaque hemorrhage (IPH) were assessed. The correlation of the plaque characteristics between intracranial and extracranial carotid arteries was determined.

resultsIn total, 107 patients (mean age: 57.0 ± 11.1 years, 69 males) were recruited. In discriminating intracranial severe stenosis (≥50% stenosis), the odds ratio (OR) of Max WT of extracranial carotid arteries was 1.41 (95% confidence interval [CI], 0.94-2.11,

interpretationCarotid artery plaque burden is significantly associated with severe intracranial artery stenosis, suggesting that extracranial carotid plaque burden might be an independent indicator for severity of intracranial artery atherosclerosis.

Identifiers

PMID30009201
PMCPMC6043773
OpenAlexW2805223371

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.