Evidence map›Paper›PMID 30027504›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2020

Long-term prognostic value of low-dose normal stress-only myocardial perfusion imaging by wide beam reconstruction: A competing risk analysis.

Carmela Nappi, Wanda Acampa, Emanuele Nicolai, Stefania Daniele, Emilia Zampella, Roberta Assante, Valeria Gaudieri, Teresa Mannarino, Mario Petretta, Alberto Cuocolo

Abstract read
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In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Prognostic Value of Coronary Flow Capacity byCirculation. Cardiovascular imaging · 2024
    Article
  2. Article
  3. Prognostic value of heart rate reserve in patients with suspected coronary artery disease undergoing stress myocardial perfusion imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  4. Computed tomography calls out nuclear imaging in its field: It doesn't matter how you are searching but what you are looking for.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  5. Simultaneous dual-tracerJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  6. Temporal trends of abnormal myocardial perfusion imaging in a cohort of Italian subjects: Relation with cardiovascular risk factors.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020
    Article
  7. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Carmela NappiDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, 80131, Naples, Italy.
Wanda AcampaDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, 80131, Naples, Italy.
Emanuele NicolaiIRCCS-SDN, Naples, Italy.
Stefania DanieleInstitute of Biostructure and Bioimaging, National Council of Research, Naples, Italy.
Emilia ZampellaDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, 80131, Naples, Italy.
Roberta AssanteDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, 80131, Naples, Italy.
Valeria GaudieriInstitute of Biostructure and Bioimaging, National Council of Research, Naples, Italy.
Teresa MannarinoDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, 80131, Naples, Italy.
Mario PetrettaDepartment of Translational Medical Sciences, University Federico II, Naples, Italy.
Alberto CuocoloDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, 80131, Naples, Italy. cuocolo@unina.it.
Federico II University Hospital · ITInstitute of Biostructure and Bioimaging · ITSDN Istituto di Ricerca Diagnostica e Nucleare · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA normal stress myocardial perfusion single-photon emission computed tomography (MPS) is associated with a good clinical outcome. New iterative algorithms, such as wide beam reconstruction (WBR), which improve image interpretation with half-dose or half-time acquisition, have been proposed for cardiac MPS. The aim of this study was to assess the long-term predictive value of a low-dose normal stress-only MPS with WBR using conventional Anger camera in patients with known or suspected coronary artery disease (CAD). METHODS AND

resultsA total of 2106 patients with known or suspected CAD and normal perfusion at half-dose stress-only MPS protocol were followed for a mean of 6.6 ± 2.7 years. MPS data were reconstructed with WBR iterative algorithm. End-point events were cardiac death or nonfatal myocardial infarction. Noncardiac death was considered the competing event. During follow-up, 149 cardiac events occurred with an annualized event rate of 1.2%. Independent predictors of cardiac events at Cox analysis were age, male gender, diabetes mellitus, previous myocardial infarction and the need for pharmacologic stress testing. At Fine-Gray analysis the cumulative incidence of cardiac events progressively increases with age and in the presence of diabetes for any combination of gender and stress type. Survival tree analysis confirmed that long-term prognosis considerably varies according of risk factors profile.

conclusionsLow-dose normal stress-only WBR MPS has a reliable long-term prognostic value in patients with suspected or known CAD. This finding supports the introduction of such a method into clinical practice with a consistent dose optimization in the interest of patients and exposed staff.

Indexed as

Myocardial Perfusion ImagingAgedAlgorithmsCoronary Artery DiseaseExercise TestFemaleFollow-Up StudiesHeartHumansImage Processing, Computer-AssistedIncidenceMaleMiddle AgedMyocardial InfarctionMyocardial RevascularizationPerfusionTechnetium Tc 99m Sestamibidiagnostic and prognostic applicationMPISPECT

Identifiers

PMID30027504
OpenAlexW2883745322

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.