Evidence map›Paper›PMID 30030826›Full record

ReviewAdvances in experimental medicine and biology2018

Integration of Drosophila and Human Genetics to Understand Notch Signaling Related Diseases.

Jose L Salazar, Shinya Yamamoto

Open access · greenAbstract readReview
In one paragraph

Review in Advances in experimental medicine and biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
10.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 43 citations in OpenAlex.

  1. Review
  2. Review
  3. Quantifying bristle cell organization inbioRxiv : the preprint server for biology · 2025
    Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
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  12. Review
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  16. Review
  17. International journal of molecular sciences · 2021
    Review
  18. Model matchmaking.Lab animal · 2021
    Article
  19. Effect of NTN and Lmx1Parkinson's disease · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jose L SalazarDepartment of Molecular and Human Genetics, Baylor College of Medicine (BCM), Houston, TX, USA.
Shinya YamamotoDepartment of Molecular and Human Genetics, Baylor College of Medicine (BCM), Houston, TX, USA. yamamoto@bcm.edu.
Baylor College of Medicine · US

Funding

Initiative for Maximizing Student Development (IMSD) ProgramR25GM056929 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI PEREIRA, FRED A · 1998 to 2023
$12.4M
Zebrafish CoreU54NS093793 · NINDS · BAYLOR COLLEGE OF MEDICINE · PI BELLEN, HUGO J · 2015 to 2022
$7.5M
PROGRAM IN HUMAN MOLECULAR GENETICST32GM008307 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI SHAULSKY, GAD · 1990 to 2020
$6.6M
Genomic medicine and gene function implementation for an underserved populationR01HG011795 · NHGRI · BAYLOR COLLEGE OF MEDICINE · PI BELLEN, HUGO J, WANGLER, MICHAEL FRANCIS · 2021 to 2025
$4.8M
NHGRI NIH HHS R01 HG011795NIGMS NIH HHS R25 GM056929NIGMS NIH HHS T32 GM008307NINDS NIH HHS U54 NS093793
6 · The paper itself

Abstract

Notch signaling research dates back to more than one hundred years, beginning with the identification of the Notch mutant in the fruit fly Drosophila melanogaster. Since then, research on Notch and related genes in flies has laid the foundation of what we now know as the Notch signaling pathway. In the 1990s, basic biological and biochemical studies of Notch signaling components in mammalian systems, as well as identification of rare mutations in Notch signaling pathway genes in human patients with rare Mendelian diseases or cancer, increased the significance of this pathway in human biology and medicine. In the 21

Indexed as

Drosophila ProteinsGenetic Diseases, InbornNeoplasm ProteinsNeoplasmsReceptors, NotchAnimalsDrosophila melanogasterHumansSignal TransductionDrosophila ProteinsNeoplasm ProteinsN protein, DrosophilaReceptors, NotchDrosophilaFunctional genomicsMendelian diseasesNotch signalingTranslational research

Identifiers

PMID30030826
PMCPMC6233323
OpenAlexW2883080885

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.