Evidence map›Paper›PMID 30039919›Full record

ReviewJournal of cellular and molecular medicine2018

The dual role of N6-methyladenosine modification of RNAs is involved in human cancers.

Liujia He, Jiangfeng Li, Xiao Wang, Yufan Ying, Haiyun Xie, Huaqing Yan, Xiangyi Zheng, Liping Xie

Abstract readReview
In one paragraph

Review in Journal of cellular and molecular medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Emerging Roles of mFrontiers in oncology · 2022
    Pooled it
  2. RNA modifications and cancer ferroptosis.Cancer cell international · 2026
    Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. The impact of YTHDF2-mediated NCOA4 methylation on myocardial ferroptosis.Apoptosis : an international journal on programmed cell death · 2025
    Article
  9. Article
  10. FTO-mediated mTranslational cancer research · 2025
    Article
  11. Review
  12. Discovery of CRBN-recruiting PROTAC degraders of the METTL3-METTL14 complex.Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents · 2025
    Article
  13. Review
  14. Article
  15. Non-coding RNA-Mediated N6-Methyladenosine (mNon-coding RNA research · 2024
    Review
  16. The mFrontiers in pharmacology · 2024
    Review
  17. Comprehensive analysis of mEpigenetics · 2023
    Article
  18. Article
  19. Article
  20. New insights on the interaction between mWorld journal of surgical oncology · 2023
    Article

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Liujia HeDepartment of Urology, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Jiangfeng LiDepartment of Urology, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Xiao WangDepartment of Urology, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Yufan YingDepartment of Urology, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Haiyun XieDepartment of Urology, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Huaqing YanDepartment of Urology, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Xiangyi ZhengDepartment of Urology, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.ORCID 0000-0002-9428-1514
Liping XieDepartment of Urology, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As the most abundant and reversible RNA modification in eukaryotic cells, m

Indexed as

Epigenesis, GeneticGene Expression Regulation, NeoplasticRNA EditingAdenosineAlkB Homolog 5, RNA DemethylaseAlpha-Ketoglutarate-Dependent Dioxygenase FTOCarcinogenesisDisease ProgressionGenetic TherapyHumansMethylationMethyltransferasesMolecular Targeted TherapyNeoplasmsRNA, NeoplasmAdenosineALKBH5 protein, humanAlkB Homolog 5, RNA DemethylaseAlpha-Ketoglutarate-Dependent Dioxygenase FTOFTO protein, humanMethyltransferasesMETTL3 protein, humanN-methyladenosineRNA, NeoplasmALKBH5cancerepigeneticsFTOMETTL3N6-methyladenosine (m6A)

Identifiers

PMID30039919
PMCPMC6156243

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.