Evidence mapPaperPMID 30044293Full record

Trial reportAnesthesia and analgesia2018

Preoperative Continuation Versus Interruption of Oral Hypoglycemics in Type 2 Diabetic Patients Undergoing Ambulatory Surgery: A Randomized Controlled Trial.

Irina Gasanova, Jin Meng, Abu Minhajuddin, Emily Melikman, John C Alexander, Girish P Joshi

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Anesthesia and analgesia, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04284722 (Perioperative Continuation of Metformin Therapy in Patients With Typ 2 Diabetes Mellitus Undergoing Non-cardiac Surgery), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04284722 phase4unknown statusstarted 2020, after this paper: background citation

Perioperative Continuation of Metformin Therapy in Patients With Typ 2 Diabetes Mellitus Undergoing Non-cardiac Surgery

Ran2020Enrolled400Registered outcomes8Posted comparisons0ConditionsHyperglycemia, Hyperlactatemia, Metformin, Type 2 DiabetesArmsMetformin hydrochloride
PMID 28940961PMID 20393934PMID 30958402other papers from this trial
Open the trial in the graph
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Recent advances in diabetes treatments and their perioperative implications.Current opinion in anaesthesiology · 2019 · on this map
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Irina GasanovaFrom the Departments of Anesthesiology and Pain Management.
Jin MengFrom the Departments of Anesthesiology and Pain Management.
Abu MinhajuddinClinical Sciences, University of Texas Southwestern Medical Center, Dallas, Texas.
Emily MelikmanFrom the Departments of Anesthesiology and Pain Management.
John C AlexanderFrom the Departments of Anesthesiology and Pain Management.
Girish P JoshiFrom the Departments of Anesthesiology and Pain Management.
Pain Management Institute · USThe University of Texas Southwestern Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with type 2 diabetes mellitus receiving oral hypoglycemic drugs (OHDs) are usually instructed to stop them before surgery. We hypothesize that continuing OHD preoperatively should result in lower perioperative blood glucose (BG) levels. Ambulatory surgery patients with type 2 diabetes mellitus on OHDs were randomized to continue (n = 69) or withhold (n = 73) OHDs preoperatively. Log-transformed BG levels at pre-, intra-, and postoperative periods were analyzed. Perioperative BG levels were significantly lower (mean, 138 mg/dL; 95% confidence interval, 130-146 mg/dL) in the group that continued versus the group that discontinued OHDs (mean, 156 mg/dL; 95% confidence interval, 146-167 mg/dL; P < .001).

Indexed as

Ambulatory Surgical ProceduresPerioperative CareAdministration, OralAdultAgedBiomarkersBlood GlucoseDiabetes Mellitus, Type 2Drug Administration ScheduleFemaleHumansHypoglycemic AgentsMaleMetforminMiddle AgedRisk AssessmentBiomarkersBlood GlucoseHypoglycemic AgentsMetforminSulfonylurea Compounds

Identifiers

PMID30044293
OpenAlexW2883841245

What Socratic holds

Texttitle and abstract
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.