Evidence map›Paper›PMID 30045964›Full record

ArticlemSphere2018

The Third Transmembrane Domain of EscR Is Critical for Function of the Enteropathogenic

Irit Tseytin, Adi Madar, Bosko Mitrovic, Wanyin Deng, B Brett Finlay, Neta Sal-Man

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Irit Tseytin *Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Be'er Sheva, Israel.
Adi Madar *Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Be'er Sheva, Israel.
Bosko MitrovicShraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Be'er Sheva, Israel.
Wanyin DengMichael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada.
B Brett FinlayMichael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada.
Neta Sal-ManShraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Be'er Sheva, Israel salmanne@bgu.ac.il.ORCID 0000-0002-1109-479X
Ben-Gurion University of the Negev · ILUniversity of British Columbia · CA

Funding

CIHR
6 · The paper itself

Abstract

Many Gram-negative bacterial pathogens utilize a specialized protein delivery system, called the type III secretion system (T3SS), to translocate effector proteins into the host cells. The translocated effectors are crucial for bacterial infection and survival. The base of the T3SS transverses both bacterial membranes and contains an export apparatus that comprises five membrane proteins. Here, we study the export apparatus of enteropathogenic

Indexed as

Enteropathogenic Escherichia coliMutant ProteinsMutation, MissenseProtein DomainsProtein MultimerizationType III Secretion SystemsMutant ProteinsType III Secretion Systemsenteropathogenic E. coliexport apparatusinner membrane proteinstransmembrane domaintype III secretion system

Identifiers

PMID30045964
PMCPMC6060343
OpenAlexW2884924025

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.