ArticleNature genetics2018
The maize W22 genome provides a foundation for functional genomics and transposon biology.
Article in Nature genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 115 papers.
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Who cites it
115 citing papers in PubMed, 251 citations in OpenAlex.
- Graph-based pan-genome reveals structural and functional diversity across oil palm domestication gradients.BMC plant biology · 2026Article
- High-quality chromosome-scale genome assemblies of 29 maize inbred lines of European breeding relevance.Scientific data · 2026Article
- A distributive germline restricts the spread of new mutations.bioRxiv : the preprint server for biology · 2026Article
- Near-complete genome assembly of a transformation-efficient elite inbred line LH244 and its comparison with B73.Journal of integrative plant biology · 2026Article
- Chromosome-level genome assemblies of two maize inbred lines with contrasting plant architectures.Scientific data · 2026Article
- The repetitive genome of the Ixodes ricinus tick reveals transposable elements have driven genome evolution in ticks.Genome biology · 2026Article
- Assay of Ds2 Transposition Activity in the Maize W22.microPublication biology · 2026Article
- Callus and endosperm green fluorescence reporter-assisted selection system in maize CRISPR/Cas9 gene editing.BMC plant biology · 2025Article
- Decades' progress and prospects on maize functional genomics and molecular breeding.Science China. Life sciences · 2025Review
- Adaptive sampling with Oxford Nanopore offers a simple way to improve the efficiency of plant metagenomic studies.The New phytologist · 2025Article
- Genetic variation at transcription factor binding sites largely explains phenotypic heritability in maize.Nature genetics · 2025Article
- Quantitative and sensitive sequencing of somatic mutations induced by a maize transposon.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- MDR1 DNA glycosylase regulates the expression of genomically imprinted genes and Helitrons.The Plant journal : for cell and molecular biology · 2025Article
- Increased maize chromosome number by engineered chromosome fission.Science advances · 2025Article
- Global modulation of gene expression and transcriptome size in aneuploid combinations of maize.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Conservation of imprinted expression across genotypes is correlated with consistency of imprinting across endosperm development in maize.G3 (Bethesda, Md.) · 2025Article
- A multidisciplinary and integrative review of the structural genome and epigenome of Capsicum L. species.Planta · 2025Review
- Transcriptome profiling of maize transcription factor mutants to probe gene regulatory network predictions.G3 (Bethesda, Md.) · 2025Article
- MaizeCODE reveals bi-directionally expressed enhancers that harbor molecular signatures of maize domestication.Nature communications · 2024Article
- Review
55 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
54 authors at 16 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The maize W22 inbred has served as a platform for maize genetics since the mid twentieth century. To streamline maize genome analyses, we have sequenced and de novo assembled a W22 reference genome using short-read sequencing technologies. We show that significant structural heterogeneity exists in comparison to the B73 reference genome at multiple scales, from transposon composition and copy number variation to single-nucleotide polymorphisms. The generation of this reference genome enables accurate placement of thousands of Mutator (Mu) and Dissociation (Ds) transposable element insertions for reverse and forward genetics studies. Annotation of the genome has been achieved using RNA-seq analysis, differential nuclease sensitivity profiling and bisulfite sequencing to map open reading frames, open chromatin sites and DNA methylation profiles, respectively. Collectively, the resources developed here integrate W22 as a community reference genome for functional genomics and provide a foundation for the maize pan-genome.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.