ArticleAlimentary pharmacology & therapeutics2018
Incidence, prevalence and clinical outcome of anaemia in inflammatory bowel disease: a population-based cohort study.
Article in Alimentary pharmacology & therapeutics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
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Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- Molecular Mechanisms Underlying the Higher Prevalence of Anemia in Crohn's Disease Compared with Ulcerative Colitis: A Systematic Review.International journal of molecular sciences · 2026Pooled it
- Risk factors of inflammatory bowel disease complicating anemia: A systematic review and meta-analysis.Medicine · 2026Pooled it
- Oral Sucrosomial Iron Is as Effective as Intravenous Ferric Carboxy-Maltose in Treating Anemia in Patients with Ulcerative Colitis.Nutrients · 2021Trial
- The Gut Microbial Metabolite Indole-3-Acetic Acid Reprograms Systemic Homeostasis and Ameliorates IBD-Associated Cachexia Independent of Food Intake.International journal of molecular sciences · 2025Article
- Anemia in Inflammatory Bowel Disease: Practice Patterns and Clinical Outcomes in a Large National Veterans Cohort.Crohn's & colitis 360 · 2025Article
- Nutritional status and prevalence of anemia in patients with Crohn's disease after surgery: a multicenter cross-sectional study in China.Frontiers in nutrition · 2025Article
- Risk of heart failure in inflammatory bowel disease: a Swedish population-based study.European heart journal · 2024Article
- Are Internet Information Sources Helpful for Adult Crohn's Disease Patients Regarding Nutritional Advice?Journal of clinical medicine · 2024Article
- Potential Diagnostic Role of Hepcidin in Anemic Patients Affected by Inflammatory Bowel Disease: A Systematic Review.Diagnostics (Basel, Switzerland) · 2024Review
- Anemia and Iron Deficiency in Outpatients with Inflammatory Bowel Disease: Ubiquitous Yet Suboptimally Managed.Journal of clinical medicine · 2022Article
- Review
- Black Race and Public Insurance Are Predictive of Inappropriate Evaluation of Iron Deficiency Anemia and Diarrhea.Digestive diseases and sciences · 2021Article
- Observational
- Hypophosphatemia after high-dose intravenous iron treatment in patients with inflammatory bowel disease: Mechanisms and possible clinical impact.World journal of gastroenterology · 2021Observational
- Iron Deficiency Anemia in Inflammatory Bowel Disease: What Do We Know?Frontiers in medicine · 2021Review
- Prediction of outcome of treatment of acute severe ulcerative colitis using principal component analysis and artificial intelligence.JGH open : an open access journal of gastroenterology and hepatology · 2020Article
- Bacterial Lipopolysaccharides Suppress Erythroblastic Islands and Erythropoiesis in the Bone Marrow in an Extrinsic and G- CSF-, IL-1-, and TNF-Independent Manner.Frontiers in immunology · 2020Article
- Perioperative Surgical Home Model Improves Outcomes in Crohn's Disease Patients Undergoing Disease-Related Surgery.Gastroenterology research and practice · 2020Article
- Efficacy of iron supplementation in patients with inflammatory bowel disease treated with anti-tumor necrosis factor-alpha agents.Therapeutic advances in gastroenterology · 2020Article
- Anemia is associated with the risk of Crohn's disease, not ulcerative colitis: A nationwide population-based cohort study.PloS one · 2020Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe incidence and short-term outcome of anaemia in inflammatory bowel disease (IBD) are largely unknown.
aimTo determine the incidence, prevalence and clinical outcome of anaemia in terms of resolution of anaemia within 12 months. We also planned to assess risk factors for anaemia in IBD.
methodsA random sample of 342 patients was obtained from the population-based IBD cohort of Örebro University Hospital, Sweden, consisting of 1405 patients diagnosed between 1963 and 2010. Haemoglobin measurements recorded from 1 January 2011 to 31 December 2013 were extracted from the Clinical Chemistry data system.
resultsIn Crohn's disease, the incidence rate of anaemia was 19.3 (95% CI: 15.4-23.7) per 100 person-years and the prevalence was 28.7% (CI: 22.0-36.2), compared with 12.9 (CI: 9.8-16.5) and 16.5% (CI: 11.2-22.9) for ulcerative colitis. Crohn's disease was associated with an increased incidence (OR = 1.60; CI: 1.02-2.51) and prevalence of anaemia (OR = 2.04; CI: 1.20-3.46) compared to ulcerative colitis. Stricturing disease phenotype in Crohn's disease (HR = 2.59; CI: 1.00-6.79) and extensive disease in ulcerative colitis (HR = 2.40; CI: 1.10-5.36) were associated with an increased risk of anaemia. Despite a higher probability of receiving specific therapy within 3 months from the diagnosis of anaemia, Crohn's disease patients had a worse outcome in terms of resolution of anaemia within 12 months (56% vs 75%; P = 0.03).
conclusionsAnaemia is a common manifestation of IBD even beyond the first years after the diagnosis of IBD. Crohn's disease is associated with both an increased risk and a worse outcome.
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