Evidence map›Paper›PMID 30076201›Full record

ArticleThe Journal of cell biology2018

Integrated control of formin-mediated actin assembly by a stationary inhibitor and a mobile activator.

Mikael V Garabedian, Tatiana Stanishneva-Konovalova, Chenyu Lou, Thomas J Rands, Luther W Pollard, Olga S Sokolova, Bruce L Goode

Abstract read
In one paragraph

Article in The Journal of cell biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. ADPact: A versatile sensor for ADP-F-actin.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Article
  4. Septin Organization and Dynamics for Budding Yeast Cytokinesis.Journal of fungi (Basel, Switzerland) · 2024
    Review
  5. Length control emerges from cytoskeletal network geometry.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Length control emerges from cytoskeletal network geometry.bioRxiv : the preprint server for biology · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Genetically inspired in vitro reconstitution ofMolecular biology of the cell · 2020
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mikael V GarabedianDepartment of Biology, Rosenstiel Basic Medical Science Research Center, Brandeis University, Waltham, MA.
Tatiana Stanishneva-KonovalovaBioengineering Department, Faculty of Biology, Lomonosov Moscow State University, Moscow, Russia.ORCID 0000-0002-8427-8178
Chenyu LouDepartment of Biology, Rosenstiel Basic Medical Science Research Center, Brandeis University, Waltham, MA.
Thomas J RandsDepartment of Biology, Rosenstiel Basic Medical Science Research Center, Brandeis University, Waltham, MA.
Luther W PollardDepartment of Biology, Rosenstiel Basic Medical Science Research Center, Brandeis University, Waltham, MA.
Olga S SokolovaBioengineering Department, Faculty of Biology, Lomonosov Moscow State University, Moscow, Russia.
Bruce L GoodeDepartment of Biology, Rosenstiel Basic Medical Science Research Center, Brandeis University, Waltham, MA goode@brandeis.edu.ORCID 0000-0002-6443-5893

Funding

Quantitative Neuroscience: Tools for Bridging Levels of AnalysisT32NS007292 · NINDS · BRANDEIS UNIVERSITY · PI GINA G TURRIGIANO · 1986 to 2026
$12.7M
GENETIC AND BIOCHEMICAL MECHANISMS OF REGULATIONT32GM007122 · NIGMS · BRANDEIS UNIVERSITY · PI LOVETT, SUSAN THOMAS · 1985 to 2020
$7.5M
Regulation of formins and cell polarity in yeastR01GM083137 · NIGMS · BRANDEIS UNIVERSITY · PI GOODE, BRUCE L · 2008 to 2019
$4.3M
NIGMS NIH HHS R01 GM083137NIGMS NIH HHS T32 GM007122NINDS NIH HHS T32 NS007292
6 · The paper itself

Abstract

Formins are essential actin assembly factors whose activities are controlled by a diverse array of binding partners. Until now, most formin ligands have been studied on an individual basis, leaving open the question of how multiple inputs are integrated to regulate formins in vivo. Here, we show that the F-BAR domain of

Indexed as

Protein MultimerizationActinsAnimalsCytoskeletal ProteinsMicrofilament ProteinsMicrotubule-Associated ProteinsProtein DomainsRabbitsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSecretory VesiclesActinsBNR1 protein, S cerevisiaeBUD6 protein, S cerevisiaeCytoskeletal ProteinsHOF1 protein, S cerevisiaeMicrofilament ProteinsMicrotubule-Associated ProteinsSaccharomyces cerevisiae Proteins

Identifiers

PMID30076201
PMCPMC6168263

What Socratic holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.