Evidence map›Paper›PMID 30086746›Full record

ReviewJournal of biomedical science2018

Genetic influence alters the brain synchronism in perception and timing.

Victor Marinho, Thomaz Oliveira, Juliete Bandeira, Giovanny R Pinto, Anderson Gomes, Valéria Lima, Francisco Magalhães, Kaline Rocha, Carla Ayres, Valécia Carvalho and 6 more

Open access · diamondAbstract readReview
In one paragraph

Review in Journal of biomedical science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. The Role of the Serotonergic System in Time Perception: A Systematic Review.International journal of molecular sciences · 2024
    Pooled it
  2. VNTR Polymorphisms in theBioengineering (Basel, Switzerland) · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 2 countries.

Victor MarinhoNeuro-innovation Technology & Brain Mapping Laboratory, Federal University of Piauí, Av. São Sebastião n° 2819 - Nossa Sra. de Fátima -, Parnaíba, PI, CEP 64202-020, Brazil. victormarinhophb@hotmail.com.
Thomaz OliveiraNeuro-innovation Technology & Brain Mapping Laboratory, Federal University of Piauí, Av. São Sebastião n° 2819 - Nossa Sra. de Fátima -, Parnaíba, PI, CEP 64202-020, Brazil.
Juliete BandeiraNeuro-innovation Technology & Brain Mapping Laboratory, Federal University of Piauí, Av. São Sebastião n° 2819 - Nossa Sra. de Fátima -, Parnaíba, PI, CEP 64202-020, Brazil.
Giovanny R PintoGenetics and Molecular Biology Laboratory, Federal University of Piauí, Parnaíba, Brazil.
Anderson GomesGenetics and Molecular Biology Laboratory, Federal University of Piauí, Parnaíba, Brazil.
Valéria LimaGenetics and Molecular Biology Laboratory, Federal University of Piauí, Parnaíba, Brazil.
Francisco MagalhãesNeuro-innovation Technology & Brain Mapping Laboratory, Federal University of Piauí, Av. São Sebastião n° 2819 - Nossa Sra. de Fátima -, Parnaíba, PI, CEP 64202-020, Brazil.
Kaline RochaNeuro-innovation Technology & Brain Mapping Laboratory, Federal University of Piauí, Av. São Sebastião n° 2819 - Nossa Sra. de Fátima -, Parnaíba, PI, CEP 64202-020, Brazil.
Carla AyresNeuro-innovation Technology & Brain Mapping Laboratory, Federal University of Piauí, Av. São Sebastião n° 2819 - Nossa Sra. de Fátima -, Parnaíba, PI, CEP 64202-020, Brazil.
Valécia CarvalhoNeuro-innovation Technology & Brain Mapping Laboratory, Federal University of Piauí, Av. São Sebastião n° 2819 - Nossa Sra. de Fátima -, Parnaíba, PI, CEP 64202-020, Brazil.
Bruna VelasquesBrain Mapping and Sensory Motor Integration Laboratory, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Pedro RibeiroBrain Mapping and Sensory Motor Integration Laboratory, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Marco OrsiniMaster's Program in Local Development Program, University Center Augusto Motta - UNISUAM, Rio de Janeiro, Brazil and Health Sciences Applied - Vassouras University, Rio de Janeiro, Brazil.
Victor Hugo BastosBrain Mapping and Functionality Laboratory, Federal University of Piauí, Parnaíba, Brazil.
Daya GuptaDepartment of Biology, Camden County College, Blackwood, NJ, USA.
Silmar TeixeiraNeuro-innovation Technology & Brain Mapping Laboratory, Federal University of Piauí, Av. São Sebastião n° 2819 - Nossa Sra. de Fátima -, Parnaíba, PI, CEP 64202-020, Brazil.
Universidade Federal do Piauí · BRUniversidade Federal do Rio de Janeiro · BRCamden County College · USUniversity Center Augusto Motta · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStudies at the molecular level aim to integrate genetic and neurobiological data to provide an increasingly detailed understanding of phenotypes related to the ability in time perception. MAIN TEXT: This study suggests that the polymorphisms genetic SLC6A4 5-HTTLPR, 5HTR2A T102C, DRD2/ANKK1-Taq1A, SLC6A3 3'-UTR VNTR, COMT Val158Met, CLOCK genes and GABRB2 A/C as modification factor at neurochemical levels associated with several neurofunctional aspects, modifying the circadian rhythm and built-in cognitive functions in the timing. We conducted a literature review with 102 studies that met inclusion criteria to synthesize findings on genetic polymorphisms and their influence on the timing.

conclusionThe findings suggest an association of genetic polymorphisms on behavioral aspects related in timing. However, order to confirm the paradigm of association in the timing as a function of the molecular level, still need to be addressed future research.

Indexed as

Genetic Predisposition to DiseaseAdultCircadian RhythmCognitionDopamine Plasma Membrane Transport ProteinsFemaleGenetic Association StudiesGenotypeHumansMalePolymorphism, Single NucleotideProtein Serine-Threonine KinasesReceptors, Dopamine D2Serotonin Plasma Membrane Transport ProteinsTime PerceptionANKK1 protein, humanDopamine Plasma Membrane Transport ProteinsProtein Serine-Threonine KinasesReceptors, Dopamine D2Serotonin Plasma Membrane Transport ProteinsSLC6A3 protein, humanSLC6A4 protein, humanCircadian rhythmDopamineGABAGenetic polymorphismsSerotoninTime perception

Identifiers

PMID30086746
PMCPMC6080374
OpenAlexW2887599943

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.