ReviewJournal of pharmacopuncture2017
Review on Clinical Trials of Black Seed (Nigella sativa ) and Its Active Constituent, Thymoquinone.
Review in Journal of pharmacopuncture, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
77 citing papers in PubMed, 3 syntheses or guidelines pooled it, 216 citations in OpenAlex.
- Cold pressed oils: a systematic review on physicochemical properties, nutritional composition and pharmacological activities.Frontiers in nutrition · 2026Pooled it
- Effect ofTheScientificWorldJournal · 2020Pooled it
- Effect of Nigella sativa and its bioactive compound on type 2 epithelial to mesenchymal transition: a systematic review.BMC complementary and alternative medicine · 2019Pooled it
- The Effect of Short Treatment with Nigella Sativa on Symptoms, the Cluster of Differentiation (CD) Profile, and Inflammatory Markers in Mild COVID-19 Patients: A Randomized, Double-Blind Controlled Trial.International journal of environmental research and public health · 2022Trial
- Trial
- Modulation of Nrf2/TNF-α and TLR4/TGF-β1 Signaling Pathways by Nigella Sativa Oil and Echinacea Purpurea Extract Attenuates Cyclosporine A-Induced Nephrotoxicity and Immunotoxicity.Cell biochemistry and biophysics · 2026Article
- Defined Natural Products as Adjunctive Therapies: Evidence-Gated Polypharmacology Across Molecular Targets, Human Exposure, Clinical Signals, and Safety Boundaries.International journal of molecular sciences · 2026Review
- Enhancement of tobramycin and amikacin activities by co-encapsulation in liposomal-thymoquinone formulation: antibacterial, antibiofilm, and cytocompatibility study.Therapeutic delivery · 2026Article
- Advances in Chemotherapy in Pediatrics Acute Lymphocytic Leukemia (Pall): Actions, Associated Risks and Emerging Therapies.Current pharmaceutical design · 2026Review
- Ameliorative Role of EthanolicVeterinary medicine international · 2026Article
- Review
- Bisphenol A-Induced Vascular Endothelial Dysfunction: Protective Effects ofFood science & nutrition · 2025Article
- Thymoquinone Attenuates NF-κβ Signalling Activation in Retinal Pigment Epithelium Cells Under AMD-Mimicking Conditions.International journal of molecular sciences · 2025Article
- Clinical Uses of Nigella Sativa in Pediatrics: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2025Article
- Black Cumin Seed (Food science & nutrition · 2025Article
- Functional, Nutraceutical, and Pharmacological Properties of Black Seed.Food science & nutrition · 2025Review
- Discovery of Species-Specific Peptide Markers for Superseed Authentication Using Targeted LC-MS/MS Proteomics.Molecules (Basel, Switzerland) · 2025Article
- Synthesis of Chitosan based nanoemulsions and their characterization and antifungal activity toward fungi causing mucormycosis.Scientific reports · 2025Article
- The protective effect of various forms ofFrontiers in nutrition · 2025Article
- Antimicrobial Properties and Therapeutic Potential of Bioactive Compounds inMolecules (Basel, Switzerland) · 2024Review
17 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectives
methodsPubMed-Medline, Scopus, and Web of Science databases were searched to identify randomized control trials (RCTs) investigating the therapeutic effects of
resultsBlack seed and TQ are shown to possess multiple useful effects for the treatment of patients with several diseases, such as inflammatory and auto-immune disorders, as well as metabolic syndrome. Also, other advantages, including antimicrobial, anti-nociceptive and anti-epileptic properties, have been documented. The side effects of this herbal medicine appear not to be serious, so it can be applied in clinical trials because of its many advantages.
conclusionSome effects of
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.