Evidence map›Paper›PMID 30097067›Full record

Trial reportJournal of the International Society of Sports Nutrition2018

Citrulline malate supplementation does not improve German Volume Training performance or reduce muscle soreness in moderately trained males and females.

Andrew J Chappell, Daniel M Allwood, Rebecca Johns, Samantha Brown, Kiran Sultana, Annie Anand, Trevor Simper

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of the International Society of Sports Nutrition, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 41 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Andrew J ChappellFood and Nutrition group, Sheffield Business School, Sheffield Hallam University, Stoddard Building, City Campus, Sheffield, UK. a.chappell@shu.ac.uk.ORCID http://orcid.org/0000-0003-3999-9395
Daniel M AllwoodDepartment of Biosciences and Chemistry, Sheffield Hallam University, Owen Building, City Campus, Sheffield, UK.
Rebecca JohnsFood and Nutrition group, Sheffield Business School, Sheffield Hallam University, Stoddard Building, City Campus, Sheffield, UK.
Samantha BrownFood and Nutrition group, Sheffield Business School, Sheffield Hallam University, Stoddard Building, City Campus, Sheffield, UK.
Kiran SultanaFood and Nutrition group, Sheffield Business School, Sheffield Hallam University, Stoddard Building, City Campus, Sheffield, UK.
Annie AnandFood and Nutrition group, Sheffield Business School, Sheffield Hallam University, Stoddard Building, City Campus, Sheffield, UK.
Trevor SimperFood and Nutrition group, Sheffield Business School, Sheffield Hallam University, Stoddard Building, City Campus, Sheffield, UK.
Sheffield Hallam University · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUse of supplements to aid performance is common practice amongst recreationally active individuals, including those without a sufficient evidence base. This investigation sought to assess whether acute supplementation with 8 g of citrulline malate (CM) (1.11: 1 ratio) would improve anaerobic performance.

methodsA randomised double blind placebo control trial was employed, using a counterbalanced design. We recruited recreationally active men and women to take part in an isokinetic chair protocol, based on German Volume Training (GVT) whereby participants attempted to perform 10 sets of 10 repetitions against a force representing 70% of their peak concentric force.

resultsThe number of repetitions achieved over the course of the GVT was 94.0 ± 7.9 and 90.9 ± 13.9 for placebo and CM respectively. There was no significant difference between the placebo and CM treatment for number of repetitions (P = 0.33), isometric (P = 0.60), concentric (P = 0.38), or eccentric (P = 0.65) peak force following the GVT. Total muscle soreness was significantly higher in the CM compared to the placebo treatment following the GVT protocol over 72 h (P = 0.01); although this was not accompanied by a greater workload/number of repetitions in the CM group.

conclusionsWe conclude that an acute dose of CM does not significantly affect anaerobic performance using an isokinetic chair in recreational active participants. Practical implications include precaution in recommending CM supplementation. Coaches and athletes should be aware of the disparity between the chemical analyses of the products reviewed in the present investigation versus the manufacturers' claims.

Indexed as

Dietary SupplementsAdultCitrullineCross-Over StudiesDouble-Blind MethodFemaleHumansLactic AcidMalatesMaleMuscle, SkeletalMuscle StrengthMuscle Strength DynamometerMyalgiaYoung AdultCitrullinecitrulline malateLactic AcidMalatesAnaerobic exerciseCitrulline malateGVTIsometric forceLactateMuscle sorenessReturn of force

Identifiers

PMID30097067
PMCPMC6086018
OpenAlexW2887417714

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.