Trial reportDiabetes, obesity & metabolism2019
The impact of food order on postprandial glycaemic excursions in prediabetes.
Trial report in Diabetes, obesity & metabolism, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05121844 (Use of Continuous Glucose Monitoring in Non-Diabetic Population to Compliment Signos Mobile Health Platform), which is not on this map. Cited by 40 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Use of Continuous Glucose Monitoring in Non-Diabetic Population to Compliment Signos Mobile Health Platform: Comprehensive Weight Optimization Program and Customized Lifestyle Modifications
Who cites it
40 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Efficacy of a meal sequence in patients with type 2 diabetes: a systematic review and meta-analysis.BMJ open diabetes research & care · 2022Pooled it
- Dietary Modification with Food Order and Divided Carbohydrate Intake Improves Glycemic Excursions in Healthy Young Women.Nutrients · 2025Trial
- Imprecision nutrition? Intraindividual variability of glucose responses to duplicate presented meals in adults without diabetes.The American journal of clinical nutrition · 2025Trial
- Effects of a personalized nutrition program on cardiometabolic health: a randomized controlled trial.Nature medicine · 2024Trial
- A Randomized Controlled Pilot Study of the Food Order Behavioral Intervention in Prediabetes.Nutrients · 2023Trial
- Trial
- Trial
- Combination of Texture-Induced Oral Processing and Vegetable Preload Strategy Reduced Glycemic Excursion but Decreased Insulin Sensitivity.Nutrients · 2022Trial
- Acute Effects of Breakfast Fruits Meal Sequence and Postprandial Exercise on the Blood Glucose Level and DPP4 Activity among Type 2 Diabetes Mellitus Patients: A Pilot Study.Journal of obesity · 2022Trial
- Article
- Optimizing Continuous Glucose Monitoring Adoption in India: From Current Challenges to Future Solutions.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2026Review
- Bundled behavioural strategies for long-term weight maintenance in Chinese patients with overweight or obesity.Asia Pacific journal of clinical nutrition · 2025Article
- The Meal Type Rather than the Meal Sequence Affects the Meal Duration, Number of Chews, and Chewing Tempo.Nutrients · 2025Article
- Sequence of Eating at Japanese-Style Set Meals Improves Postprandial Glycemic Elevation in Healthy People.Nutrients · 2025Article
- Global burden of Type 2 Diabetes Mellitus attributable to dietary risks in elderly adults: insights from the Global Burden of Disease study 2021.Frontiers in nutrition · 2025Article
- The Impact of a Nutritional Intervention on Glycemic Control and Cardiovascular Risk Markers in Type 2 Diabetes.Nutrients · 2024Article
- Exploring the short-term impact of swapping consumption from standard protein snacks to higher protein snacks on energy intake in social drinkers: Is protein worth a nudge?Food science & nutrition · 2024Article
- Guideline for the Management of Diabetes Mellitus in the Elderly in China (2024 Edition).Aging medicine (Milton (N.S.W)) · 2024Article
- Manipulation of Post-Prandial Hyperglycaemia in Type 2 Diabetes: An Update for Practitioners.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024Review
- Nutritional Strategies for the Management of Type 2 Diabetes Mellitus: A Narrative Review.Nutrients · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
Data suggest that nutrient order during a meal significantly impacts postprandial glucose and insulin excursions in type 2 diabetes, while its effects in prediabetes have not been reported. Fifteen participants with prediabetes consumed the same meal on 3 days in random order: carbohydrate first, followed 10 minutes later by protein and vegetables (CF); protein and vegetables first, followed 10 minutes later by carbohydrate (PVF); or vegetables first followed by protein and carbohydrate (VF). Blood was sampled for glucose and insulin measurements at 0, 30, 60, 90, 120, 150 and 180 minutes. Incremental glucose peaks were similarly attenuated by >40% in the PVF and VF meal conditions compared with CF. The incremental area under the curve for glucose was 38.8% lower following the PVF meal order, compared with CF, and postprandial insulin excursions were significantly lower in the VF meal condition compared with CF. The CF meal pattern showed marked glycaemic variability whereas glucose levels were stable in the PVF and VF meal conditions. Food order presents a novel, simple behavioural strategy to reduce glycaemic excursions in prediabetes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.