Evidence map›Paper›PMID 30103400›Full record

Trial reportNutrients2018

Nutritional Metabolomics: Postprandial Response of Meals Relating to Vegan, Lacto-Ovo Vegetarian, and Omnivore Diets.

Millie Rådjursöga, Helen M Lindqvist, Anders Pedersen, B Göran Karlsson, Daniel Malmodin, Lars Ellegård, Anna Winkvist

Abstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  14. D-dimer to Creatinine Ratio: A Novel Biomarker Associated with Gensini Score in ST-Segment Elevation Myocardial Infarction Patients.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Millie RådjursögaDepartment of Internal Medicine and Clinical Nutrition, Sahlgrenska Academy, University of Gothenburg, Box 459, 405 30 Gothenburg, Sweden. millie.radjursoga@gu.se.ORCID 0000-0002-1017-3904
Helen M LindqvistDepartment of Internal Medicine and Clinical Nutrition, Sahlgrenska Academy, University of Gothenburg, Box 459, 405 30 Gothenburg, Sweden. helen.lindqvist@gu.se.ORCID 0000-0002-2627-0434
Anders PedersenSwedish NMR Centre, University of Gothenburg, Box 465, 405 30 Gothenburg, Sweden. anders.pedersen@nmr.gu.se.ORCID 0000-0001-8704-5129
B Göran KarlssonSwedish NMR Centre, University of Gothenburg, Box 465, 405 30 Gothenburg, Sweden. goran.karlsson@nmr.gu.se.
Daniel MalmodinSwedish NMR Centre, University of Gothenburg, Box 465, 405 30 Gothenburg, Sweden. daniel.malmodin@nmr.gu.se.
Lars EllegårdDepartment of Internal Medicine and Clinical Nutrition, Sahlgrenska Academy, University of Gothenburg, Box 459, 405 30 Gothenburg, Sweden. lasse.ellegard@nutrition.gu.se.
Anna WinkvistDepartment of Internal Medicine and Clinical Nutrition, Sahlgrenska Academy, University of Gothenburg, Box 459, 405 30 Gothenburg, Sweden. anna.winkvist@nutrition.gu.se.ORCID 0000-0001-9122-7240

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metabolomics provide an unbiased tool for exploring the modulation of the human metabolome in response to food intake. This study applied metabolomics to capture the postprandial metabolic response to breakfast meals corresponding to vegan (VE), lacto ovo-vegetarian (LOV), and omnivore (OM) diets. In a cross over design 32 healthy volunteers (16 men and 16 females) consumed breakfast meals in a randomized order during three consecutive days. Fasting and 3 h postprandial serum samples were collected and then subjected to metabolite profiling using ¹H-nuclear magnetic resonance (NMR) spectroscopy. Changes in concentration of identified and discriminating metabolites, between fasting and postprandial state, were compared across meals. Betaine, choline, and creatine displayed higher concentration in the OM breakfast, while 3-hydroxyisobutyrate, carnitine, proline, and tyrosine showed an increase for the LOV and unidentified free fatty acids displayed a higher concentration after the VE breakfast. Using ¹H NMR metabolomics it was possible to detect and distinguish the metabolic response of three different breakfast meals corresponding to vegan, lacto-ovo vegetarian, and omnivore diets in serum.

Indexed as

Dairy ProductsDiet, VeganDiet, VegetarianEggsEnergy MetabolismMealsNutritive ValueAdultBiomarkersCross-Over StudiesFastingFemaleHumansMaleMetabolomicsNutritional StatusBiomarkersdietshuman metabolomemetabolomicsNMRnutritionomnivorepostprandialserumveganvegetarian

Identifiers

PMID30103400
PMCPMC6115722

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.