Evidence map›Paper›PMID 30103411›Full record

ReviewInternational journal of molecular sciences2018

Murine Bone Marrow Niches from Hematopoietic Stem Cells to B Cells.

Michel Aurrand-Lions, Stéphane J C Mancini

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
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  6. Article
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  10. Review
  11. Review
  12. Article
  13. Review
  14. Deletion ofFrontiers in immunology · 2022
    Article
  15. Article
  16. Sclerostin Depletion Induces Inflammation in the Bone Marrow of Mice.International journal of molecular sciences · 2021
    Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Michel Aurrand-LionsAix Marseille University, CNRS, INSERM, Institut Paoli-Calmettes, CRCM, 13009 Marseille, France. michel.aurrand-lions@inserm.fr.
Stéphane J C ManciniAix Marseille University, CNRS, INSERM, Institut Paoli-Calmettes, CRCM, 13009 Marseille, France. stephane.mancini@inserm.fr.ORCID 0000-0001-9255-4606

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

After birth, the development of hematopoietic cells occurs in the bone marrow. Hematopoietic differentiation is finely tuned by cell-intrinsic mechanisms and lineage-specific transcription factors. However, it is now clear that the bone marrow microenvironment plays an essential role in the maintenance of hematopoietic stem cells (HSC) and their differentiation into more mature lineages. Mesenchymal and endothelial cells contribute to a protective microenvironment called hematopoietic niches that secrete specific factors and establish a direct contact with developing hematopoietic cells. A number of recent studies have addressed in mouse models the specific molecular events that are involved in the cellular crosstalk between hematopoietic subsets and their niches. This has led to the concept that hematopoietic differentiation and commitment towards a given hematopoietic pathway is a dynamic process controlled at least partially by the bone marrow microenvironment. In this review, we discuss the evolving view of murine hematopoietic⁻stromal cell crosstalk that is involved in HSC maintenance and commitment towards B cell differentiation.

Indexed as

AnimalsBone MarrowCell DifferentiationLymphopoiesisMesenchymal Stem CellsMicePrecursor Cells, B-LymphoidStem Cell NicheTranscription FactorsTranscription FactorsB lymphopoiesisbone marrow nichesearly hematopoiesisstromal cells

Identifiers

PMID30103411
PMCPMC6121419

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.