ArticleTranslational psychiatry2018
Genes associated with anhedonia: a new analysis in a large clinical trial (GENDEP).
Article in Translational psychiatry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 24 citations in OpenAlex.
- Efficacy and Safety of Toludesvenlafaxine Hydrochloride Sustained-Release Tablets in Depression With Anhedonia: A Single-Arm, Multicenter Clinical Study.Depression and anxiety · 2025Trial
- Determining cut-off values and predictors for the Snaith-Hamilton Pleasure Scale: comparison between clinical and school settings.BJPsych open · 2024Article
- The presence of anhedonia in individuals with subacute and chronic stroke: an exploratory cohort study.Frontiers in aging neuroscience · 2024Article
- Genetic Associations of Anhedonia: Insights into Overlap of Mental and Somatic Disorders.Consortium psychiatricum · 2024Article
- Sex Significantly Impacts the Function of Major Depression-Linked Variants In Vivo.Biological psychiatry · 2023Article
- Characterization of Maternal Psychosocial Stress During Pregnancy: The Healthy Start Study.Women's health reports (New Rochelle, N.Y.) · 2022Article
- Understanding Anhedonia from a Genomic Perspective.Current topics in behavioral neurosciences · 2022Review
- Progress and challenges in research of the mechanisms of anhedonia in major depressive disorder.General psychiatry · 2022Review
- Anhedonia in Depression and Schizophrenia: Brain Reward and Aversion Circuits.Neuropsychiatric disease and treatment · 2022Review
- Phenotypic and genetic associations between anhedonia and brain structure in UK Biobank.Translational psychiatry · 2021Article
- Association between GLP-1 receptor gene polymorphisms with reward learning, anhedonia and depression diagnosis.Acta neuropsychiatrica · 2020Article
- Redefining phenotypes to advance psychiatric genetics: Implications from hierarchical taxonomy of psychopathology.Journal of abnormal psychology · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors at 10 institutions in 8 countries.
Funding
Abstract
A key feature of major depressive disorder (MDD) is anhedonia, which is a predictor of response to antidepressant treatment. In order to shed light on its genetic underpinnings, we conducted a genome-wide association study (GWAS) followed by investigation of biological pathway enrichment using an anhedonia dimension for 759 patients with MDD in the GENDEP study. The GWAS identified 18 SNPs associated at genome-wide significance with the top one being an intronic SNP (rs9392549) in PRPF4B (pre-mRNA processing factor 4B) located on chromosome 6 (P = 2.07 × 10
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.