ReviewJournal of geriatric cardiology : JGC2018
Depression and chronic heart failure in the elderly: an intriguing relationship.
Review in Journal of geriatric cardiology : JGC, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 46 citations in OpenAlex.
- AIDEBMC geriatrics · 2026Trial
- Development of a predictive model of hospitalization in primary care patients with heart failure.PloS one · 2019Trial
- Trial
- Heart failure types and predictors of 30-day rehospitalisation among patients aged ≥ 60 years with acute heart failure: a multicentre prospective study in Vietnam.BMC cardiovascular disorders · 2025Article
- The relationship between depression and cardiovascular disease in older people: results from a large-scale epidemiological cohort study in Japan.European geriatric medicine · 2025Article
- Using the 5Ms Framework to Advance Aging-Responsive Care for Heart Failure with Reduced Ejection Fraction.Clinical interventions in aging · 2025Review
- The Relation between Parameters of Physical Performance and Depression in Consecutive Hospitalized Geriatric Patients with Heart Failure.Nutrients · 2024Article
- Impact of COVID-19 on the Mental Health of Elderly Patients at Midnapore Medical College, West Bengal.Cureus · 2024Article
- Clinical intervention effect of Xuefu Zhuyu decoction on chronic heart failure complicated with depression.World journal of psychiatry · 2024Article
- Depression, anxiety, and quality of life as predictors of rehospitalization in patients with chronic heart failure.BMC cardiovascular disorders · 2023Observational
- Depression Predicts Cardiac Cachexia in Heart Failure Patients.Biological research for nursing · 2023Article
- The Prevalence of Depression and Anxiety in Heart Failure Patients in Saudi Arabia: An Original Study.Cureus · 2023Article
- Chinese expert consensus on the diagnosis and treatment of chronic heart failure in elderly patients (2021).Aging medicine (Milton (N.S.W)) · 2022Article
- Focal points of preanesthesia evaluations for electroconvulsive therapy in patients with depression: a retrospective analysis of clinical characteristics in nonremission.BMC anesthesiology · 2022Article
- Psychological difficulties of LVAD patients and caregivers: A follow up over one year from discharge.Artificial organs · 2022Observational
- Mechanism of tonifying-kidney Chinese herbal medicine in the treatment of chronic heart failure.Frontiers in cardiovascular medicine · 2022Review
- Application Value of NT-proBNP Combined with NLR in Evaluation of Major Adverse Cardiac Events in Elderly Patients with Chronic Heart Failure.Emergency medicine international · 2022Article
- Cognitive impairment and depression in heart failure: 'cardiological giants'.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2021Article
- Recognition of cognitive impairment and depressive symptoms in older patients with heart failure.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2021Article
- Burden and Quality of Life Among Female and Male Patients with Heart Failure in Europe: A Real-World Cross-Sectional Study.Patient preference and adherence · 2021Article
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic heart failure and depressive disorders have a high prevalence and incidence in the elderly. Several studies have shown how depression tends to exacerbate coexisting chronic heart failure and its clinical outcomes and vice versa, especially in the elderly. The negative synergism between chronic heart failure and depression in the elderly may be approached only taking into account the multifaceted pathophysiological characteristics underlying both these conditions, such as behavioural factors, neurohormonal activation, inflammatory mediators, hypercoagulability and vascular damage. Nevertheless, the pathophysiological link between these two conditions is not well established yet. Despite the high prevalence of depression in chronic heart failure elderly patients and its negative prognostic value, it is often unrecognized especially because of shared symptoms. So the screening of mood disorders, using reliable questionnaires, is recommended in elderly patients with chronic heart failure, even if cannot substitute a diagnostic interview by mental health professionals. In this setting, treatment of depression requires a multidisciplinary approach including: psychotherapy, antidepressants, exercise training and electroconvulsive therapy. Pharmacological therapy with selective serotonin reuptake inhibitors, despite conflicting results, improves quality of life but does not guarantee better outcomes. Exercise training is effective in improving quality of life and prognosis but at the same time cardiac rehabilitation services are vastly underutilized.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.