Evidence map›Paper›PMID 30109010›Full record

ArticleMedChemComm2018

Discovery of a tetrazolyl β-carboline with

Anirudha Karvande, Shahnawaz Khan, Irfan Khan, Deepti Singh, Vikram Khedgikar, Priyanka Kushwaha, Naseer Ahmad, Priyanka Kothari, Anupam Dhasmana, Ruchir Kant and 2 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in MedChemComm, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 6 countries.

Anirudha KarvandeEndocrinology Division , CSIR-Central Drug Research Institute (CSIR-CDRI) , Lucknow , 226031 , India . Email: ritu_trivedi@cdri.res.in.
Shahnawaz KhanChemistry Division , BHUPAL NOBLES' UNIVERSITY , Udaipur-313001 , India.
Irfan KhanMedicinal and Process Chemistry Division , CSIR-Central Drug Research Institute , Lucknow-226031 , U.P , India . Email: pms_chauhan@cdri.res.in.
Deepti SinghMedicinal and Process Chemistry Division , CSIR-Central Drug Research Institute , Lucknow-226031 , U.P , India . Email: pms_chauhan@cdri.res.in.
Vikram KhedgikarEndocrinology Division , CSIR-Central Drug Research Institute (CSIR-CDRI) , Lucknow , 226031 , India . Email: ritu_trivedi@cdri.res.in.
Priyanka KushwahaEndocrinology Division , CSIR-Central Drug Research Institute (CSIR-CDRI) , Lucknow , 226031 , India . Email: ritu_trivedi@cdri.res.in.
Naseer AhmadEndocrinology Division , CSIR-Central Drug Research Institute (CSIR-CDRI) , Lucknow , 226031 , India . Email: ritu_trivedi@cdri.res.in.
Priyanka KothariEndocrinology Division , CSIR-Central Drug Research Institute (CSIR-CDRI) , Lucknow , 226031 , India . Email: ritu_trivedi@cdri.res.in.
Anupam DhasmanaResearch Himalayan School of Bio sciences , Swami Rama Himalayan University , Dehradun , India.
Ruchir KantMolecular and Structural Biology Central Drug Research Institute , CSIR , Lucknow 226031 , India.
Ritu TrivediEndocrinology Division , CSIR-Central Drug Research Institute (CSIR-CDRI) , Lucknow , 226031 , India . Email: ritu_trivedi@cdri.res.in.ORCID 0000-0002-9524-2541
Prem M S ChauhanMedicinal and Process Chemistry Division , CSIR-Central Drug Research Institute , Lucknow-226031 , U.P , India . Email: pms_chauhan@cdri.res.in.ORCID 0000-0002-2780-1305
Central Drug Research Institute · INDivision of Chemistry · USSwami Rama Himalayan University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

β-Carbolines have been assessed for osteoclastogenesis. However, their effect on osteoblasts during estrogen deficiency is still unclear. Here, a series of novel piperazine and tetrazole tag β-carbolines have been synthesized and examined for osteoblast differentiation

Identifiers

PMID30109010
PMCPMC6072419
OpenAlexW2808117802

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.