SynthesisPancreas2018
Preexisting Diabetes Elevates Risk of Local and Systemic Complications in Acute Pancreatitis: Systematic Review and Meta-analysis.
Synthesis in Pancreas, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 68 citations in OpenAlex.
- Metabolic syndrome components individually worsen the outcome of acute pancreatitis: a systematic review and meta-analysis.Frontiers in endocrinology · 2025Pooled it
- Risk factors for diabetes mellitus after acute pancreatitis: a systematic review and meta-analysis.Frontiers in medicine · 2023Pooled it
- Fluid resuscitation in the early management of acute pancreatitis: a five-year retrospective observational study.World journal of emergency medicine · 2026Article
- Associations between dietary patterns and diabetes in patients with acute pancreatitis: a cross-sectional analysis from the DREAM study.Nutrition journal · 2026Observational
- The Acid Test - Does Ketoacidosis Affect the Course and Prognosis of Hypertriglyceridemic Acute Pancreatitis?Digestive diseases and sciences · 2026Article
- Impact of Diabetes Mellitus on Disease Severity and Mortality in Acute Pancreatitis: A Retrospective Single-Center Cohort Study.Journal of clinical medicine · 2026Article
- The association between serum HbA1c and infected pancreatic necrosis in acute necrotizing pancreatitis.BMC gastroenterology · 2025Article
- Impact of Metabolic Surgery on the Severity and Outcomes of Acute Pancreatitis: A Retrospective Matched Cohort Study.Obesity surgery · 2025Article
- TRMT6 and TRMT61A facilitated acute pancreatitis severity via regulation of neutrophil function.Science China. Life sciences · 2025Article
- The 12-Year Experience of the Hungarian Pancreatic Study Group.Journal of clinical medicine · 2025Review
- Predictive Value of Several Parameters for Severity of Acute Pancreatitis in a Cohort of 172 Patients.Diagnostics (Basel, Switzerland) · 2025Article
- Impact of metabolic syndrome components on clinical outcomes in hypertriglyceridemia-induced acute pancreatitis.World journal of gastroenterology · 2024Article
- Acute Pancreatitis and Type 2 Diabetes Mellitus: The Chicken-Egg Paradox-A Seven-Year Experience of a Large Tertiary Center.Journal of clinical medicine · 2024Article
- Clinical Outcomes of Diabetes Mellitus on Moderately Severe Acute Pancreatitis and Severe Acute Pancreatitis.Journal of inflammation research · 2024Article
- Metabolic-associated fatty liver disease is associated with acute pancreatitis with more severe course: Post hoc analysis of a prospectively collected international registry.United European gastroenterology journal · 2023Article
- Impact of comorbidities on hospital mortality in patients with acute pancreatitis: a population-based study of 110,021 patients.BMC gastroenterology · 2023Article
- A retrospective study on comparison of clinical characteristics and outcomes of diabetic ketoacidosis patients with and without acute pancreatitis.Scientific reports · 2023Observational
- Elevated serum HbA1c level, rather than previous history of diabetes, predicts the disease severity and clinical outcomes of acute pancreatitis.BMJ open diabetes research & care · 2023Article
- Article
- New-onset diabetes secondary to acute pancreatitis: An update.World journal of clinical cases · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The prevalence of diabetes mellitus (DM) and acute pancreatitis (AP) increases continuously, therefore, to understand the effects of preexisting diabetes on AP is crucially needed. Here, we performed a systematic review and meta-analysis in which AP patients including DM and non-DM groups were sorted. Several outcome parameters were analyzed, and the odds ratio (OR) and standardized mean difference with 95% confidence intervals (CIs) were calculated.We found 1417 articles, of which 9 articles involving 354,880 patients were analyzed. More complications were seen in diabetic patients than in non-DM patients (OR, 1.553 [95% CI, 1.266-1.904]; P < 0.001). Intensive care unit admission (OR, 1.799 [95% CI, 1.442-2.243]; P < 0.001) and renal failure (OR, 1.585 [95% CI, 1.278-1.966]; P < 0.001) were more frequent in DM patients. There was a tendency of higher mortality and local complications (OR, 1.276 [95% CI, 0.991-1.643]; P = 0.059; and OR, 1.267 [95% CI, 0.964-1.659]; P = 0.090, respectively) in preexisting DM. Length of hospitalization was longer in DM patients (standardized mean difference, 0.217 [95% CI, 0.075-0.360]; P = 0.003). Preexisting DM negatively influences the outcome of AP and increases the risk of renal failure, local complications, and mortality.
Indexed as
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.