Evidence map›Paper›PMID 30117343›Full record

SynthesisIntegrative cancer therapies2018

Clinical Benefits of Acupuncture for the Reduction of Hormone Therapy-Related Side Effects in Breast Cancer Patients: A Systematic Review.

Yuanqing Pan, Kehu Yang, Xiue Shi, Haiqian Liang, Xiping Shen, Renjie Wang, Li Ma, Qi Cui, Runze Yu, Yi Dong

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Integrative cancer therapies, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
5.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Yuanqing Pan1 Tianjin Medical College, Tianjin, China.
Kehu Yang2 Lanzhou University, Lanzhou, Gansu, China.
Xiue Shi3 Gansu Rehabilitation Center Hospital, Lanzhou, China.
Haiqian Liang4 Tianjin Pingjin Hospital, Tianjin, China.
Xiping Shen2 Lanzhou University, Lanzhou, Gansu, China.
Renjie Wang4 Tianjin Pingjin Hospital, Tianjin, China.
Li Ma5 General Hospital of Tianjin Medical University, Tianjin, China.
Qi Cui6 The First Affiliated Hospital of Lanzhou University, Lanzhou, Gansu, China.
Runze Yu1 Tianjin Medical College, Tianjin, China.
Yi Dong1 Tianjin Medical College, Tianjin, China.
Lanzhou University · CNTianjin Medical University · CNPingjin Hospital · CNGansu Provincial Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

importanceAcupuncture can help reduce unpleasant side effects associated with endocrine therapy for breast cancer. Nevertheless, comprehensive evaluation of current evidence from randomized controlled trials(RCTs) is lacking.

objectiveTo estimate the efficacy of acupuncture for the reduction of hormone therapy-related side effects in breast cancer patients. EVIDENCE REVIEW: RCTs of acupuncture in breast cancer patients that examined reductions in hormone therapy-related side effects were retrieved from PubMed, EMBASE, Web of Science, Ovid MEDLINE, and Cochrane Library databases through April 2016. The quality of the included studies was evaluated according to the 5.2 Cochrane Handbook standards, and CONSORT and STRICTA (Revised Standards for Reporting Interventions in Clinical Trials of Acupuncture) statements.

interventionInterventions included conventional acupuncture treatment compared with no treatment, placebo, or conventional pharmaceutical medication. Major outcome measures were the alleviation of frequency and symptoms and the presence of hormone therapy-related side effects. Findings/Results. A total of 17 RCTs, including a total of 810 breast cancer patients were examined. The methodological quality of the trials was relatively rigorous in terms of randomization, blinding, and sources of bias. Compared with control therapies, the pooled results suggested that acupuncture had moderate effects in improving stiffness. No significant differences were observed in hot flashes, fatigue, pain, gastrointestinal symptoms, Kupperman index, general well-being, physical well-being, tumor necrosis factor (TNF), and interleukin (IL).

conclusionsAcupuncture therapy appears to be potentially useful in relieving functional stiffness. However, further large-sample trials with evidence-based design are still needed to confirm these findings.

Indexed as

AcupunctureAnimalsBreast NeoplasmsClinical Trials as TopicFemaleHormone Replacement TherapyHumansacupuncturebreast cancerhormone therapy–related side effectsquality of lifesystematic review

Identifiers

PMID30117343
PMCPMC6142070
OpenAlexW2886522327

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.