Evidence map›Paper›PMID 30133134›Full record

Trial reportMolecular nutrition & food research2018

Cinnamyl Isobutyrate Decreases Plasma Glucose Levels and Total Energy Intake from a Standardized Breakfast: A Randomized, Crossover Intervention.

Christina M Hochkogler, Julia K Hoi, Barbara Lieder, Nicole Müller, Joachim Hans, Sabine Widder, Jakob P Ley, Veronika Somoza

Open access · hybridAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Molecular nutrition & food research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Christina M HochkoglerChristian Doppler Laboratory for Bioactive Aroma Compounds, Faculty of Chemistry, University of Vienna, Althanstraße 14, 1090, Vienna, Austria.
Julia K HoiChristian Doppler Laboratory for Bioactive Aroma Compounds, Faculty of Chemistry, University of Vienna, Althanstraße 14, 1090, Vienna, Austria.
Barbara LiederDepartment of Physiological Chemistry, Faculty of Chemistry, University of Vienna, Althanstraße 14, 1090, Vienna, Austria.
Nicole MüllerChristian Doppler Laboratory for Bioactive Aroma Compounds, Faculty of Chemistry, University of Vienna, Althanstraße 14, 1090, Vienna, Austria.
Joachim HansSymrise AG, Muehlenfeldstraße 1, 37603, Holzminden, Germany.
Sabine WidderSymrise AG, Muehlenfeldstraße 1, 37603, Holzminden, Germany.
Jakob P LeySymrise AG, Muehlenfeldstraße 1, 37603, Holzminden, Germany.
Veronika SomozaChristian Doppler Laboratory for Bioactive Aroma Compounds, Faculty of Chemistry, University of Vienna, Althanstraße 14, 1090, Vienna, Austria.
Symrise (Germany) · DEUniversity of Vienna · ATChristian Doppler Laboratory for Thermoelectricity · AT

Funding

Austrian Federal Ministry for Digital and Economic AffairsNational Foundation for Research, Technology and DevelopmentSymrise AG
6 · The paper itself

Abstract

scopeCinnamon is associated with anti-obesity effects, regulating food intake, improving plasma glucose levels and lipid profiles in vivo. In the present study, the impact of cinnamyl isobutyrate (CIB), one constituent of cinnamon, on ad libitum food intake from a standardized breakfast and outcome measures of hormonal regulation of appetite were investigated. METHODS AND

resultsIn this randomized, short-term crossover intervention study, a 75 g per 300 mL glucose solution solely (control) or supplemented with 0.45 mg CIB was administered to 26 healthy volunteers. Prior to and 2 h after receiving control or CIB treatment, subjective hunger perceptions were rated using a visual analog scale. Food intake from a standardized breakfast was assessed 2 h after treatments. Plasma peptide YY

conclusionsCIB, administered at a 0.45 mg bolus in 75 g glucose-water solution, decreased ad libitum energy intake from a standardized breakfast and postprandial plasma glucose levels.

Indexed as

AdultBlood GlucoseBreakfastCinnamatesDietary SupplementsEnergy IntakeGhrelinGlucagon-Like Peptide 1Glucose Tolerance TestHumansInsulinMaleNutrientsOverweightPostprandial PeriodSatiationBlood GlucoseCinnamatescinnamyl isobutyrateGhrelinGlucagon-Like Peptide 1InsulinNutrientsSerotoninblood glucosecinnamyl isobutyrateenergy intakesatietyserotonin

Identifiers

PMID30133134
PMCPMC6175204
OpenAlexW2888116183

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.